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CD4 immunoadhesin — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/CD4_immunoadhesin
License (as archived): CC-BY-SA-4.0
Archived: 2026-10-06T16:40:23.138Z
SHA-256 of the archived text: efb7067c8b85e567f6d474a03b0db9beb086d12aa9780fc5639a79f84366309d
Stable URL of this page: https://metraipolis.com/documento/dc_fcdbe28e56fe

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CD4 immunoadhesin — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/CD4_immunoadhesin (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_fcdbe28e56fe (Metraipolis archive dc_fcdbe28e56fe, sha256 efb7067c8b85e567f6d474a03b0db9beb086d12aa9780fc5639a79f84366309d)

BibTeX

@misc{dcfcdbe28e56fe,
  title = {CD4 immunoadhesin — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/CD4_immunoadhesin},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_fcdbe28e56fe; sha256 efb7067c8b85e567f6d474a03b0db9beb086d12aa9780fc5639a79f84366309d},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/CD4_immunoadhesin. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

CD4 immunoadhesin is a recombinant fusion protein consisting of a combination of CD4 and the fragment crystallizable region, similarly known as immunoglobulin. It belongs to the antibody (Ig) gene family. CD4 is a surface receptor for human immunodeficiency virus (HIV). The CD4 immunoadhesin molecular fusion allow the protein to possess key functions from each independent subunit. The CD4 specific properties include the gp120-binding and HIV-blocking capabilities. Properties specific to immunoglobulin are the long plasma half-life and Fc receptor binding. The properties of the protein means that it has potential to be used in AIDS therapy as of 2017. Specifically, CD4 immunoadhesin plays a role in antibody-dependent cell-mediated cytotoxicity (ADCC) towards HIV-infected cells. While natural anti-gp120 antibodies exhibit a response towards uninfected CD4-expressing cells that have a soluble gp120 bound to the CD4 on the cell surface, CD4 immunoadhesin, however, will not exhibit a response. One of the most relevant of these possibilities is its ability to cross the placenta.

Tema degli esploratori: scienze della vita e salute (deposito sistematico; categoria «Immunology»).
Fonte: Wikipedia in inglese, voce «CD4 immunoadhesin» — https://en.wikipedia.org/wiki/CD4_immunoadhesin
Wikidata Q5009823 (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q5009823
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/CD4_immunoadhesin?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1374075662, consultata il 2026-10-06T15:18:31.053Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: cef9287518b948318b69d68220e1dbf42b8cf0959e6fae851587c2e2ef601ba6