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4-Hydroxy-3-methoxyamphetamine — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/4-Hydroxy-3-methoxyamphetamine
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-06T15:51:19.128Z
SHA-256 of the archived text: 46f8b0ee7e7b1761a3392cc488170a47619aaa446a9d0334ec1ea71eda0a1207
Stable URL of this page: https://metraipolis.com/documento/dc_fa882ff698a4

How to cite

4-Hydroxy-3-methoxyamphetamine — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/4-Hydroxy-3-methoxyamphetamine (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_fa882ff698a4 (Metraipolis archive dc_fa882ff698a4, sha256 46f8b0ee7e7b1761a3392cc488170a47619aaa446a9d0334ec1ea71eda0a1207)

BibTeX

@misc{dcfa882ff698a4,
  title = {4-Hydroxy-3-methoxyamphetamine — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/4-Hydroxy-3-methoxyamphetamine},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_fa882ff698a4; sha256 46f8b0ee7e7b1761a3392cc488170a47619aaa446a9d0334ec1ea71eda0a1207},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/4-Hydroxy-3-methoxyamphetamine. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

4-Hydroxy-3-methoxyamphetamine (HMA), also known as 3-O-methyl-α-methyldopamine, is an active metabolite of 3,4-methylenedioxymethamphetamine (MDMA). It is substantially less potent than MDMA or 3,4-methylenedioxyamphetamine (MDA) as a monoamine releasing agent in vitro. Nonetheless, HMA has been found to induce the release of serotonin, norepinephrine, and dopamine with EC50Tooltip half-maximal effective concentration values of 897 nM, 694 nM, and 1450–3423 nM, respectively, and hence acts as a lower-potency serotonin–norepinephrine–dopamine releasing agent (SNDRA). The predicted log P of HMA is 0.6.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «4-Hydroxy-3-methoxyamphetamine» — https://en.wikipedia.org/wiki/4-Hydroxy-3-methoxyamphetamine
Wikidata Q131345338: «MDMA metabolite» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q131345338
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/4-Hydroxy-3-methoxyamphetamine?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1382739606, consultata il 2026-11-06T15:42:22.106Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: a561cdd834a5a26698b4208764a75b3f44bf0db2c323ae19cbd089e16ea62cf9