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Novel mechanistic insights underlying fungal allergic inflammation — Europe PMC PMID:37703276

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/37703276
DOI: 10.1371/journal.ppat.1011623
License (as archived): CC0-1.0
Archived: 2026-10-07T12:26:53.938Z
SHA-256 of the archived text: 7874c5c051704ada3d8db351e78a359dcdb3997eb609c4a1832d6c28cd43b9c2
Stable URL of this page: https://metraipolis.com/documento/dc_f98085ecb8a6

How to cite

Novel mechanistic insights underlying fungal allergic inflammation — Europe PMC PMID:37703276 — Europe PMC (en), https://europepmc.org/article/MED/37703276 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_f98085ecb8a6 (Metraipolis archive dc_f98085ecb8a6, sha256 7874c5c051704ada3d8db351e78a359dcdb3997eb609c4a1832d6c28cd43b9c2)

BibTeX

@misc{dcf98085ecb8a6,
  title = {Novel mechanistic insights underlying fungal allergic inflammation — Europe PMC PMID:37703276},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/37703276},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_f98085ecb8a6; sha256 7874c5c051704ada3d8db351e78a359dcdb3997eb609c4a1832d6c28cd43b9c2},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/37703276. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

The worldwide prevalence of asthma and allergic disorders (allergic rhinitis, atopic dermatitis, food allergy) has been steadily rising in recent decades. It is now estimated that up to 20% of the global population is afflicted by an allergic disease, with increasing incidence rates in both high- and low-income countries. The World Allergy Organization estimates that the total economic burden of asthma and allergic rhinitis alone is approximately $21 billion per year. While allergic stimuli are a complex and heterogenous class of inputs including parasites, pollens, food antigens, drugs, and metals, it has become clear that fungi are major drivers of allergic disease, with estimates that fungal sensitization occurs in 20-30% of atopic individuals and up to 80% of asthma patients. Fungi are eukaryotic microorganisms that can be found throughout the world in high abundance in both indoor and outdoor environments. Understanding how and why fungi act as triggers of allergic type 2 inflammation will be crucial for combating this important health problem. In recent years, there have been significant advances in our understanding of fungi-induced type 2 immunity, however there is still much we don't understand, including why fungi have a tendency to induce allergic reactions in the first place. Here, we will discuss how fungi trigger type 2 immune responses and posit why this response has been evolutionarily selected for induction during fungal encounter.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: PLoS pathogens, 2023 (prima pubblicazione 2023-09-13).
Identificativi: PMID 37703276 · PMCID PMC10499257 · DOI 10.1371/journal.ppat.1011623.
Descrittori MeSH principali: Asthma; Rhinitis, Allergic.
Pagina: https://europepmc.org/article/MED/37703276 — https://doi.org/10.1371/journal.ppat.1011623. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-10-07T11:59:26.188Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.