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Neutralization of ricin toxin on building interior surfaces using liquid decontaminants — Europe PMC PMID:38722908

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/38722908
DOI: 10.1371/journal.pone.0302967
License (as archived): CC0-1.0
Archived: 2026-10-06T18:31:54.124Z
SHA-256 of the archived text: 9f3e55335e61a0a48ad23502d6851f4c8b62eb1e77c513b4e5e2dadbc10d9610
Stable URL of this page: https://metraipolis.com/documento/dc_f0ca20ebcd50

How to cite

Neutralization of ricin toxin on building interior surfaces using liquid decontaminants — Europe PMC PMID:38722908 — Europe PMC (en), https://europepmc.org/article/MED/38722908 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_f0ca20ebcd50 (Metraipolis archive dc_f0ca20ebcd50, sha256 9f3e55335e61a0a48ad23502d6851f4c8b62eb1e77c513b4e5e2dadbc10d9610)

BibTeX

@misc{dcf0ca20ebcd50,
  title = {Neutralization of ricin toxin on building interior surfaces using liquid decontaminants — Europe PMC PMID:38722908},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/38722908},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_f0ca20ebcd50; sha256 9f3e55335e61a0a48ad23502d6851f4c8b62eb1e77c513b4e5e2dadbc10d9610},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/38722908. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Ricin is a highly toxic protein, capable of inhibiting protein synthesis within cells, and is produced from the beans of the Ricinus communis (castor bean) plant. Numerous recent incidents involving ricin have occurred, many in the form of mailed letters resulting in both building and mail sorting facility contamination. The goal of this study was to assess the decontamination efficacy of several commercial off-the-shelf (COTS) cleaners and decontaminants (solutions of sodium hypochlorite [bleach], quaternary ammonium, sodium percarbonate, peracetic acid, and hydrogen peroxide) against a crude preparation of ricin toxin. The ricin was inoculated onto four common building materials (pine wood, drywall joint tape, countertop laminate, and industrial carpet), and the decontaminants were applied to the test coupons using a handheld sprayer. Decontamination efficacy was quantified using an in-vitro cytotoxicity assay to measure the quantity of bioactive ricin toxin extracted from test coupons as compared to the corresponding positive controls (not sprayed with decontaminant). Results showed that decontamination efficacy varied by decontaminant and substrate material, and that efficacy generally improved as the number of spray applications or contact time increased. The solutions of 0.45% peracetic acid and the 20,000-parts per million (ppm) sodium hypochlorite provided the overall best decontamination efficacy. The 0.45% peracetic acid solution achieved 97.8 to 99.8% reduction with a 30-min contact time.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: PloS one, 2024 (prima pubblicazione 2024-05-09).
Identificativi: PMID 38722908 · PMCID PMC11081333 · DOI 10.1371/journal.pone.0302967.
Descrittori MeSH principali: Ricin; Decontamination.
Pagina: https://europepmc.org/article/MED/38722908 — https://doi.org/10.1371/journal.pone.0302967. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-10-06T16:55:36.247Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.