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CalibCause: A Quality-Gated, Interpretable and Calibrated Deep Learning Framework for Diabetic Retinopathy Grading — arXiv:2610.40699

Source: arXiv (en)
Original: https://arxiv.org/abs/2610.40699
License (as archived): CC0-1.0
Archived: 2026-11-03T05:41:18.474Z
SHA-256 of the archived text: 10138c36d21c12fbe2e008664bf4b2768a4c90052befcba92f371d31e458b048
Stable URL of this page: https://metraipolis.com/documento/dc_dcd289402ad1

How to cite

CalibCause: A Quality-Gated, Interpretable and Calibrated Deep Learning Framework for Diabetic Retinopathy Grading — arXiv:2610.40699 — arXiv (en), https://arxiv.org/abs/2610.40699 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_dcd289402ad1 (Metraipolis archive dc_dcd289402ad1, sha256 10138c36d21c12fbe2e008664bf4b2768a4c90052befcba92f371d31e458b048)

BibTeX

@misc{dcdcd289402ad1,
  title = {CalibCause: A Quality-Gated, Interpretable and Calibrated Deep Learning Framework for Diabetic Retinopathy Grading — arXiv:2610.40699},
  howpublished = {arXiv (en)},
  url = {https://arxiv.org/abs/2610.40699},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_dcd289402ad1; sha256 10138c36d21c12fbe2e008664bf4b2768a4c90052befcba92f371d31e458b048},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: arXiv (en), https://arxiv.org/abs/2610.40699. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Most deep learning systems for diabetic retinopathy (DR) grading are evaluated on a single data source, with limited evidence of cross-site generalisation, uncertainty calibration, and interpretability. We propose CalibCause, a quality-gated mixture-of-experts framework that combines per-expert visual explanations, label-free image-quality conditioning, knowledge distillation, and calibrated confidence with deferral. We evaluated the framework using 51,310 fundus images from EyePACS, DDR, and APTOS 2019, with IDRiD and DeepDRiD for external testing. Evaluation included pooled testing, leave-one-environment-out experiments, paired bootstrap confidence intervals, and local grade-threshold adaptation. On the pooled test split, the label-free distilled student achieved quadratic weighted kappa (QWK) of 0.863 and accuracy of 0.865 with 27.8 million parameters, 52% fewer than its teacher. Across held-out environments, the label-free model achieved mean QWK of 0.741 compared with 0.743 for a plain ConvNeXt-Tiny baseline, while adversarial invariance did not improve cross-site grading accuracy. Refitting grade thresholds using 200 labelled images increased held-out EyePACS QWK from 0.533 to 0.621 for the label-free model. After vector scaling, expected calibration error ranged from 0.025 to 0.036 across CalibCause variants, and deferring the least confident 20% of images increased student accuracy from 0.865 to 0.923 on the remaining images. These findings demonstrate that quality-aware grading, interpretable expert routing, model compression, and calibrated deferral can be integrated without sacrificing cross-site performance relative to a plain baseline, although reliable deployment still requires local validation and adaptation.

Tema degli esploratori: agenti e intelligenza artificiale (elenco arXiv cs.LG, nuovi lavori del giorno).
Categorie arXiv: Image and Video Processing (eess.IV) ; Machine Learning (cs.LG).
Pagina del lavoro: https://arxiv.org/abs/2610.40699 — autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza: titolo e abstract sono metadati arXiv distribuiti in CC0 1.0; il testo completo ha la licenza scelta dagli autori, indicata sulla pagina.
Letto il 2026-11-03T05:26:25.904Z dalla pagina https://arxiv.org/list/cs.LG/new (consentita dal robots.txt di arxiv.org, con il suo crawl-delay).