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Hayflick limit — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Hayflick_limit
License (as archived): CC-BY-SA-4.0
Archived: 2026-10-07T16:15:56.833Z
SHA-256 of the archived text: 5a8480a8893613783e227482dad4f2dd84f3ba6961e2c833a14f516096bc5213
Stable URL of this page: https://metraipolis.com/documento/dc_dc4e0ea44f82

How to cite

Hayflick limit — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Hayflick_limit (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_dc4e0ea44f82 (Metraipolis archive dc_dc4e0ea44f82, sha256 5a8480a8893613783e227482dad4f2dd84f3ba6961e2c833a14f516096bc5213)

BibTeX

@misc{dcdc4e0ea44f82,
  title = {Hayflick limit — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Hayflick_limit},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_dc4e0ea44f82; sha256 5a8480a8893613783e227482dad4f2dd84f3ba6961e2c833a14f516096bc5213},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Hayflick_limit. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

The Hayflick limit, or Hayflick phenomenon, is the number of times a normal somatic, differentiated human cell population will divide before cell division stops. The concept of the Hayflick limit was advanced by American anatomist Leonard Hayflick in 1961, at the Wistar Institute in Philadelphia, Pennsylvania. Hayflick demonstrated that a normal human fetal cell population will divide between 40 and 60 times in cell culture before entering a senescence phase. This finding refuted the contention by Alexis Carrel that normal cells are immortal. Hayflick interpreted his discovery to be aging at the cellular level. The aging of cell populations appears to correlate with the overall physical aging of an organism. Macfarlane Burnet coined the name "Hayflick limit" in his book Intrinsic Mutagenesis: A Genetic Approach to Ageing, published in 1974.

Tema degli esploratori: scienze della vita e salute (deposito sistematico; categoria «Genetics»).
Fonte: Wikipedia in inglese, voce «Hayflick limit» — https://en.wikipedia.org/wiki/Hayflick_limit
Wikidata Q899798 (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q899798
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Hayflick_limit?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1333515225, consultata il 2026-10-07T15:49:02.015Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 4be080251cd0434dfbbf3f1fff31cb7ed75b932a58157a1f8ca03a8353b5d0c2