Metraipolis › archive › dc_db435ccd83dc

Persistent thermal input controls steering behavior in Caenorhabditis elegans — Europe PMC PMID:33417596

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/33417596
DOI: 10.1371/journal.pcbi.1007916
License (as archived): CC0-1.0
Archived: 2026-11-06T11:02:42.710Z
SHA-256 of the archived text: 095017ddfc9eb54c1caffdc7fa5e572f4bdf613e40dfa9a95057f04a35611089
Stable URL of this page: https://metraipolis.com/documento/dc_db435ccd83dc

How to cite

Persistent thermal input controls steering behavior in Caenorhabditis elegans — Europe PMC PMID:33417596 — Europe PMC (en), https://europepmc.org/article/MED/33417596 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_db435ccd83dc (Metraipolis archive dc_db435ccd83dc, sha256 095017ddfc9eb54c1caffdc7fa5e572f4bdf613e40dfa9a95057f04a35611089)

BibTeX

@misc{dcdb435ccd83dc,
  title = {Persistent thermal input controls steering behavior in Caenorhabditis elegans — Europe PMC PMID:33417596},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/33417596},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_db435ccd83dc; sha256 095017ddfc9eb54c1caffdc7fa5e572f4bdf613e40dfa9a95057f04a35611089},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/33417596. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Motile organisms actively detect environmental signals and migrate to a preferable environment. Especially, small animals convert subtle spatial difference in sensory input into orientation behavioral output for directly steering toward a destination, but the neural mechanisms underlying steering behavior remain elusive. Here, we analyze a C. elegans thermotactic behavior in which a small number of neurons are shown to mediate steering toward a destination temperature. We construct a neuroanatomical model and use an evolutionary algorithm to find configurations of the model that reproduce empirical thermotactic behavior. We find that, in all the evolved models, steering curvature are modulated by temporally persistent thermal signals sensed beyond the time scale of sinusoidal locomotion of C. elegans. Persistent rise in temperature decreases steering curvature resulting in straight movement of model worms, whereas fall in temperature increases curvature resulting in crooked movement. This relation between temperature change and steering curvature reproduces the empirical thermotactic migration up thermal gradients and steering bias toward higher temperature. Further, spectrum decomposition of neural activities in model worms show that thermal signals are transmitted from a sensory neuron to motor neurons on the longer time scale than sinusoidal locomotion of C. elegans. Our results suggest that employments of temporally persistent sensory signals enable small animals to steer toward a destination in natural environment with variable, noisy, and subtle cues.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: PLoS computational biology, 2021 (prima pubblicazione 2021-01-08).
Identificativi: PMID 33417596 · PMCID PMC7819614 · DOI 10.1371/journal.pcbi.1007916.
Descrittori MeSH principali: Models, Neurological.
Pagina: https://europepmc.org/article/MED/33417596 — https://doi.org/10.1371/journal.pcbi.1007916. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-11-06T10:59:03.544Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.