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Pre-exposure prophylaxis (PrEP) uptake and service delivery adaptations during the first wave of the COVID-19 pandemic in 21 PEPFAR-funded countries — Europe PMC PMID:35381024

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/35381024
DOI: 10.1371/journal.pone.0266280
License (as archived): CC0-1.0
Archived: 2026-10-19T08:07:25.727Z
SHA-256 of the archived text: 796a6400d3ee7a8bcbb3ef77d81a8916a14b7f31da2ad393e21ed45679144449
Stable URL of this page: https://metraipolis.com/documento/dc_d77dfd52b6af

How to cite

Pre-exposure prophylaxis (PrEP) uptake and service delivery adaptations during the first wave of the COVID-19 pandemic in 21 PEPFAR-funded countries — Europe PMC PMID:35381024 — Europe PMC (en), https://europepmc.org/article/MED/35381024 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_d77dfd52b6af (Metraipolis archive dc_d77dfd52b6af, sha256 796a6400d3ee7a8bcbb3ef77d81a8916a14b7f31da2ad393e21ed45679144449)

BibTeX

@misc{dcd77dfd52b6af,
  title = {Pre-exposure prophylaxis (PrEP) uptake and service delivery adaptations during the first wave of the COVID-19 pandemic in 21 PEPFAR-funded countries — Europe PMC PMID:35381024},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/35381024},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_d77dfd52b6af; sha256 796a6400d3ee7a8bcbb3ef77d81a8916a14b7f31da2ad393e21ed45679144449},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/35381024. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Background: Mitigation measures for the first wave of the COVID-19 pandemic and burden on health systems created challenges for pre-exposure prophylaxis (PrEP) service delivery. We examined PrEP uptake in PEPFAR programs before and after the start of the COVID-19 pandemic. Methods: We studied two PEPFAR program monitoring indicators, using routine Monitoring, Evaluation, Reporting (MER) indicators capturing uptake of PrEP (PrEP_NEW) and overall use of PrEP (PrEP_CURR). We also analyzed descriptive program narratives to understand successes and challenges field teams encountered after the start of the COVID-19 pandemic. To assess changes in coverage of PrEP across 21 countries, we calculated the "PrEP to need ratio" (PnR) using a published methodology. We defined the pre-COVID time period as April 1, 2019 -March 31, 2020 and the COVID time period as April 1, 2020 -March 31, 2021. Findings: The total number of persons who initiated PrEP increased by 157% from 233,250 in the pre-COVID-19 period compared with 599,935 in the COVID-19 period. All countries, except five, noted significant increases in PrEP uptake. PrEP uptake among adolescent girls and young women (AGYW) increased by 159% from 80,452 AGYW in the pre-COVID-19 period to 208,607 AGYW in the COVID-19 period. There were 77,430 key populations (KP) initiated on PrEP in the pre-COVID-19 period and 209,114 KP initiated in the COVID-19 period (a 170% increase). The PnR increased 214% in the COVID-19 period across all PEPFAR-supported countries. Adaptations, such as multi-month dispensing (MMD) of PrEP; virtual demand creation activities; decentralized, community-based and virtual service delivery, were implemented to maintain PrEP services. Conclusions: PEPFAR programs continued to maintain and initiate new clients on PrEP despite the challenges posed by the COVID-19 pandemic. Adaptations such as MMD of PrEP and use of technology were vital in expanding service delivery and increasing PrEP coverage. Funding: This project has been supported by the U.S. President's Emergency Plan for AIDS Relief.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: PloS one, 2022 (prima pubblicazione 2022-04-05).
Identificativi: PMID 35381024 · PMCID PMC8982838 · DOI 10.1371/journal.pone.0266280.
Descrittori MeSH principali: HIV Infections; Anti-HIV Agents; Pre-Exposure Prophylaxis; COVID-19.
Pagina: https://europepmc.org/article/MED/35381024 — https://doi.org/10.1371/journal.pone.0266280. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-10-19T08:03:56.770Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.