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Eosinophil — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Eosinophil
License (as archived): CC-BY-SA-4.0
Archived: 2026-10-07T15:03:46.454Z
SHA-256 of the archived text: 0b6c14df1d2a46cc0226db543a95e94fbdc2d7e8982bfcb7b7ada51aa834e4b3
Stable URL of this page: https://metraipolis.com/documento/dc_d445bc72bc7a

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Eosinophil — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Eosinophil (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_d445bc72bc7a (Metraipolis archive dc_d445bc72bc7a, sha256 0b6c14df1d2a46cc0226db543a95e94fbdc2d7e8982bfcb7b7ada51aa834e4b3)

BibTeX

@misc{dcd445bc72bc7a,
  title = {Eosinophil — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Eosinophil},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_d445bc72bc7a; sha256 0b6c14df1d2a46cc0226db543a95e94fbdc2d7e8982bfcb7b7ada51aa834e4b3},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Eosinophil. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Eosinophils, sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma. They are granulocytes that develop during hematopoiesis in the bone marrow before migrating into blood, after which they are terminally differentiated and do not multiply. These cells are eosinophilic or "acid-loving" due to their large acidophilic cytoplasmic granules, which show their affinity for acids by their affinity to coal tar dyes: Normally transparent, it is this affinity that causes them to appear brick-red after staining with eosin, a red dye, using the Romanowsky method. The staining is concentrated in small granules within the cellular cytoplasm, which contain many chemical mediators, such as eosinophil peroxidase, ribonuclease (RNase), deoxyribonucleases (DNase), lipase, plasminogen, and major basic protein. These mediators are released by a process called degranulation following activation of the eosinophil, and are toxic to both parasite and host tissues. In normal individuals, eosinophils make up about 1–3% of white blood cells, and are about 12–17 micrometres in size with bilobed nuclei. While eosinophils are released into the bloodstream, they reside in tissue. They are found in the medulla and the junction between the cortex and medulla of the thymus, and, in the lower gastrointestinal tract, ovaries, uterus, spleen, prostate, and lymph nodes, but not in the skin, lungs, esophagus, or some other internal organs under normal conditions. The presence of eosinophils in these latter organs is associated with disease. For instance, patients with eosinophilic asthma have high levels of eosinophils that lead to inflammation and tissue damage, making it more difficult for patients to breathe. Eosinophils persist in the circulation for 8–12 hours, and can survive in tissue for an additional 8–12 days in the absence of stimulation. Pioneering work in the 1980s elucidated that eosinophils were unique granulocytes, having the capacity to survive for extended periods of time after their maturation as demonstrated by ex-vivo culture experiments.

Tema degli esploratori: scienze della vita e salute (deposito sistematico; ricerca «immunology»).
Fonte: Wikipedia in inglese, voce «Eosinophil» — https://en.wikipedia.org/wiki/Eosinophil
Wikidata Q107238 (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q107238
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Eosinophil?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1371952878, consultata il 2026-10-07T14:36:57.790Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: a405567713aa9e942e442057f78d2918f163cb33ba80b524ee606a5f9c50d5c4