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Ajmaline — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Ajmaline
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-07T22:43:21.440Z
SHA-256 of the archived text: d34d2d097840e4637bff4b04c2578ae3a6c0cb5561900b0e1988d1d8ed0feea5
Stable URL of this page: https://metraipolis.com/documento/dc_cdc94253d413

How to cite

Ajmaline — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Ajmaline (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_cdc94253d413 (Metraipolis archive dc_cdc94253d413, sha256 d34d2d097840e4637bff4b04c2578ae3a6c0cb5561900b0e1988d1d8ed0feea5)

BibTeX

@misc{dccdc94253d413,
  title = {Ajmaline — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Ajmaline},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_cdc94253d413; sha256 d34d2d097840e4637bff4b04c2578ae3a6c0cb5561900b0e1988d1d8ed0feea5},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Ajmaline. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Ajmaline (also known by trade names Gilurytmal, Ritmos, and Aritmina) is an alkaloid that is classified as a 1-A antiarrhythmic agent. It is often used to induce arrhythmic contraction in patients suspected of having Brugada syndrome. Individuals suffering from Brugada syndrome will be more susceptible to the arrhythmogenic effects of the drug, and this can be observed on an electrocardiogram as an ST elevation. The compound was first isolated by Salimuzzaman Siddiqui in 1931 from the roots of Rauvolfia serpentina. He named it ajmaline, after Hakim Ajmal Khan, one of the most illustrious practitioners of Unani medicine in South Asia. Ajmaline can be found in most species of the genus Rauvolfia as well as Catharanthus roseus. In addition to Southeast Asia, Rauvolfia species have also been found in tropical regions of India, Africa, South America, and some oceanic islands. Other indole alkaloids found in Rauvolfia include reserpine, ajmalicine, serpentine, corynanthine, and yohimbine. While 86 alkaloids have been discovered throughout Rauvolfia vomitoria, ajmaline is mainly isolated from the stem bark and roots of the plant. Due to the low bioavailability of ajmaline, a semisynthetic propyl derivative called prajmaline (trade name Neo-gilurythmal) was developed that induces effects similar to those of its predecessor but which has better bioavailability and absorption.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «Ajmaline» — https://en.wikipedia.org/wiki/Ajmaline
Wikidata Q385858: «composto chimico» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q385858
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Ajmaline?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1360019893, consultata il 2026-11-07T22:39:34.498Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 43f40a9b2c8082bad911aec1acd9e0b7f9ce53d9543295e23be31623ac3dd9f7