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Artificial bone — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Artificial_bone
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-10T01:29:46.289Z
SHA-256 of the archived text: 3f67dce83dd085de3f2d5a1ffaa500ee56370784e29d4fc002d96b4e14f63cfb
Stable URL of this page: https://metraipolis.com/documento/dc_c4e9f69ced48

How to cite

Artificial bone — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Artificial_bone (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_c4e9f69ced48 (Metraipolis archive dc_c4e9f69ced48, sha256 3f67dce83dd085de3f2d5a1ffaa500ee56370784e29d4fc002d96b4e14f63cfb)

BibTeX

@misc{dcc4e9f69ced48,
  title = {Artificial bone — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Artificial_bone},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_c4e9f69ced48; sha256 3f67dce83dd085de3f2d5a1ffaa500ee56370784e29d4fc002d96b4e14f63cfb},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Artificial_bone. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Artificial bone refers to bone-like material created in a laboratory that can be used in bone grafts, to replace human bone that was lost due to severe fractures, disease, etc. Bone fracture, which is a complete or partial break in the bone, is a very common condition that has more than three million US cases per year. Human bones have the ability to regenerate themselves through the cycle of bone resorption and bone formation. The cell responsible for bone resorption is osteoclast, while the cell responsible for bone formation is osteoblast. However, if damage to bone is caused by a disease or severe injury, it becomes difficult for the body to repair itself. When the human body is unable to regenerate the lost bone tissue, surgeons replace the missing bone using autografts, allografts, and synthetic grafts (artificial bone). When comparing artificial bone to autograft and allograft, it is less invasive and more biocompatible since it avoids the risk of unknown viral infections. When designing implanted biomaterials, key criteria are biocompatibility, osteoconductivity, high porosity and biomechanics compatibility. Artificial bone was initially made of materials like metals and solid ceramics, which are strong enough to sustain the loading in bone. However, the rigidity of those materials created an enormous burden on patients and was not consistent with the criteria for implanting biomaterials. Artificial bones made of metal and ceramic tend to do poorly in terms of biocompatibility since it is difficult to blend into bone tissues. The two major components of bone are hydroxyapatite (Ca10(PO4)6(OH)2), and collagen fibers. Hydroxyapatite, which is one of the most stable forms of calcium phosphate, makes up about 60 to 65 percent of the bone. The rest of the bone is composed of materials including chondroitin sulfate, keratan sulfate and lipid. Increased research and knowledge regarding the organization, structure of properties of collagen and hydroxyapatite have led to many developments in collagen-based scaffolds in bone tissue engineering. The structure of hydroxyapatite is very similar to that of the original bone, and collagen can act as molecular cables and further improve the biocompatibility of the implant.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «Artificial bone» — https://en.wikipedia.org/wiki/Artificial_bone
Wikidata Q4801058: «bone-like material created in a laboratory that can be used in bone grafts, to replace human bone» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q4801058
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Artificial_bone?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1376104857, consultata il 2026-11-10T01:26:57.551Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 81d40d796f05be823dd26ea59234a0ca1f8d704071d5fa34e4538928450ae853