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Epistasis — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Epistasis
License (as archived): CC-BY-SA-4.0
Archived: 2026-10-08T00:13:31.354Z
SHA-256 of the archived text: f7c396d2bf2f34894565136108ad80c5c9e6e8010ded3071ad10ddfcc0816b18
Stable URL of this page: https://metraipolis.com/documento/dc_bd71c8aad0eb

How to cite

Epistasis — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Epistasis (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_bd71c8aad0eb (Metraipolis archive dc_bd71c8aad0eb, sha256 f7c396d2bf2f34894565136108ad80c5c9e6e8010ded3071ad10ddfcc0816b18)

BibTeX

@misc{dcbd71c8aad0eb,
  title = {Epistasis — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Epistasis},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_bd71c8aad0eb; sha256 f7c396d2bf2f34894565136108ad80c5c9e6e8010ded3071ad10ddfcc0816b18},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Epistasis. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Epistasis is a phenomenon in genetics in which the effect of a mutation on a trait is dependent on the presence or absence of mutations at different loci (locations on the genome), that may be on the same gene (intragenic) or on different genes, called modifier genes. In evolutionary genetics, epistasis occurs when the combined effect of two mutations is different from what you would expect by simply adding their individual effects together. This definition can be expanded to more than two loci to study higher-order epistasis, which plays an important role in shaping evolutionary trajectories. The term epistasis was introduced in 1907 to describe the discrepancy between the prediction of segregation ratios based on the action of individual genes and the actual outcome of a dihybrid cross, and is now widely used in biochemistry, computational biology and evolutionary biology. While the nuanced meaning of the term now differs between researchers studying genetics at a functional, compositional, or at a statistical level, it still describes gene interactions at various levels.

Tema degli esploratori: scienze della vita e salute (deposito sistematico; ricerca «genetics»).
Fonte: Wikipedia in inglese, voce «Epistasis» — https://en.wikipedia.org/wiki/Epistasis
Wikidata Q751748: «Fenomeno in cui una coppia di alleli copre l'espressione fenotipica di un'altra coppia» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q751748
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Epistasis?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1368823630, consultata il 2026-10-07T23:45:16.066Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 3ed1673832d2fab9e45f6c6871f035d45a0bbe8a1c4a5a3b4dba07160b2d737f