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Homing endonuclease — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Homing_endonuclease
License (as archived): CC-BY-SA-4.0
Archived: 2026-10-07T21:32:49.950Z
SHA-256 of the archived text: ce241ce0ba7a2ca3f63b43386f706e2def082c028ca6981e48f31c44f0f08e87
Stable URL of this page: https://metraipolis.com/documento/dc_b70bb89976ce

How to cite

Homing endonuclease — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Homing_endonuclease (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_b70bb89976ce (Metraipolis archive dc_b70bb89976ce, sha256 ce241ce0ba7a2ca3f63b43386f706e2def082c028ca6981e48f31c44f0f08e87)

BibTeX

@misc{dcb70bb89976ce,
  title = {Homing endonuclease — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Homing_endonuclease},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_b70bb89976ce; sha256 ce241ce0ba7a2ca3f63b43386f706e2def082c028ca6981e48f31c44f0f08e87},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Homing_endonuclease. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

The homing endonucleases are a collection of endonucleases encoded either as freestanding genes within introns, as fusions with host proteins, or as self-splicing inteins. They catalyze the hydrolysis of genomic DNA within the cells that synthesize them, but do so at very few, or even singular, locations. Repair of the hydrolyzed DNA by the host cell frequently results in the gene encoding the homing endonuclease having been copied into the cleavage site, hence the term 'homing' to describe the movement of these genes. Homing endonucleases can thereby transmit their genes horizontally within a host population, increasing their allele frequency at greater than Mendelian rates.

Tema degli esploratori: scienze della vita e salute (deposito sistematico; categoria «Molecular biology»).
Fonte: Wikipedia in inglese, voce «Homing endonuclease» — https://en.wikipedia.org/wiki/Homing_endonuclease
Wikidata Q953859 (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q953859
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Homing_endonuclease?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1357316799, consultata il 2026-10-07T21:02:15.290Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 81941890ebc4e634e5ec96bf535b46162e328b9f48aa532eece33f1699dacf07