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BFSP2 — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/BFSP2
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-10T17:11:59.045Z
SHA-256 of the archived text: 59ce5e769444df1f56b6e8ef4a2a278bfd02c25efe150e5fa3a360e5a9ae342c
Stable URL of this page: https://metraipolis.com/documento/dc_b6f514b08489

How to cite

BFSP2 — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/BFSP2 (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_b6f514b08489 (Metraipolis archive dc_b6f514b08489, sha256 59ce5e769444df1f56b6e8ef4a2a278bfd02c25efe150e5fa3a360e5a9ae342c)

BibTeX

@misc{dcb6f514b08489,
  title = {BFSP2 — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/BFSP2},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_b6f514b08489; sha256 59ce5e769444df1f56b6e8ef4a2a278bfd02c25efe150e5fa3a360e5a9ae342c},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/BFSP2. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

BFSP2 is a gene that encodes the protein phakinin ("beaded filament structural protein 2") in humans. More than 99% of the vertebrate ocular lens consists of terminally differentiated lens fiber cells. Two lens-specific intermediate filament proteins, the protein product of this gene (CP49 or phakinin) and filensin (also known as CP115), are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex. The two BFSP proteins are put into a "type VI" of intermediate filament (IF) classification. Unlike other IFs that form unbranched links, the two proteins form a network of filaments together with CRYAA.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «BFSP2» — https://en.wikipedia.org/wiki/BFSP2
Wikidata Q18032917: «gene umano» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q18032917
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/BFSP2?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1376074708, consultata il 2026-11-10T17:09:00.549Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 71d667e53832345873edb9aed31926c39fb1b9ed6ed4b96e85c1b460a51a6229