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Burden of influenza-associated respiratory hospitalizations in the Americas, 2010-2015 — Europe PMC PMID:31490961

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/31490961
DOI: 10.1371/journal.pone.0221479
License (as archived): CC0-1.0
Archived: 2026-11-10T16:23:53.997Z
SHA-256 of the archived text: 957d99fd9766b7b6c452d0cd02f2c7aaae239340db0c480b99d2ba050be7abf4
Stable URL of this page: https://metraipolis.com/documento/dc_add569db0bbf

How to cite

Burden of influenza-associated respiratory hospitalizations in the Americas, 2010-2015 — Europe PMC PMID:31490961 — Europe PMC (en), https://europepmc.org/article/MED/31490961 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_add569db0bbf (Metraipolis archive dc_add569db0bbf, sha256 957d99fd9766b7b6c452d0cd02f2c7aaae239340db0c480b99d2ba050be7abf4)

BibTeX

@misc{dcadd569db0bbf,
  title = {Burden of influenza-associated respiratory hospitalizations in the Americas, 2010-2015 — Europe PMC PMID:31490961},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/31490961},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_add569db0bbf; sha256 957d99fd9766b7b6c452d0cd02f2c7aaae239340db0c480b99d2ba050be7abf4},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/31490961. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Background: Despite having influenza vaccination policies and programs, countries in the Americas underutilize seasonal influenza vaccine, in part because of insufficient evidence about severe influenza burden. We aimed to estimate the annual burden of influenza-associated respiratory hospitalizations in the Americas. Methods: Thirty-five countries in the Americas with national influenza surveillance were invited to provide monthly laboratory data and hospital discharges for respiratory illness (International Classification of Diseases 10th edition J codes 0-99) during 2010-2015. In three age-strata (<5, 5-64, and ≥65 years), we estimated the influenza-associated hospitalizations rate by multiplying the monthly number of respiratory hospitalizations by the monthly proportion of influenza-positive samples and dividing by the census population. We used random effects meta-analyses to pool age-group specific rates and extrapolated to countries that did not contribute data, using pooled rates stratified by age group and country characteristics found to be associated with rates. Results: Sixteen of 35 countries (46%) contributed primary data to the analyses, representing 79% of the America's population. The average pooled rate of influenza-associated respiratory hospitalization was 90/100,000 population (95% confidence interval 61-132) among children aged <5 years, 21/100,000 population (13-32) among persons aged 5-64 years, and 141/100,000 population (95-211) among persons aged ≥65 years. We estimated the average annual number of influenza-associated respiratory hospitalizations in the Americas to be 772,000 (95% credible interval 716,000-829,000). Conclusions: Influenza-associated respiratory hospitalizations impose a heavy burden on health systems in the Americas. Countries in the Americas should use this information to justify investments in seasonal influenza vaccination-especially among young children and the elderly.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: PloS one, 2019 (prima pubblicazione 2019-09-06).
Identificativi: PMID 31490961 · PMCID PMC6730873 · DOI 10.1371/journal.pone.0221479.
Pagina: https://europepmc.org/article/MED/31490961 — https://doi.org/10.1371/journal.pone.0221479. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-11-10T16:21:14.800Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.