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B777-81 — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/B777-81
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-10T16:39:20.743Z
SHA-256 of the archived text: ee52492072bb2b66f69ca1948343ba5d1087f8f37e140eb1cca7e9c5b2b7eded
Stable URL of this page: https://metraipolis.com/documento/dc_aafdc4e2476e

How to cite

B777-81 — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/B777-81 (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_aafdc4e2476e (Metraipolis archive dc_aafdc4e2476e, sha256 ee52492072bb2b66f69ca1948343ba5d1087f8f37e140eb1cca7e9c5b2b7eded)

BibTeX

@misc{dcaafdc4e2476e,
  title = {B777-81 — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/B777-81},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_aafdc4e2476e; sha256 ee52492072bb2b66f69ca1948343ba5d1087f8f37e140eb1cca7e9c5b2b7eded},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/B777-81. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

B-777-81 is an antidepressant drug candidate. B777-81 works by reversing reserpine and tetrabenazine-induced ptosis in a similar manner to that of imipramine, but with a shorter duration of action. It also antagonizes reserpine-induced hypothermia but it is without effect on the decrease in locomotor activity or catalepsy following reserpine. In vitro, B777-81 inhibited 5-HT uptake in platelets, potentiated the effect of NA on isolated vas deferens and had less anticholinergic effect than imipramine in the isolated ileum.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «B777-81» — https://en.wikipedia.org/wiki/B777-81
Wikidata Q83108787: «chemical compound» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q83108787
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/B777-81?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1384047615, consultata il 2026-11-10T16:36:25.486Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 19799c2a318102f4e4bb08d43d0154014c704993c771d2b7e3a43379fb21db8a