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A comparison of all-cause and HIV cause-specific mortality among children under 5 years of age before and during COVID-19 in Kenya, 2018-2022 — Europe PMC PMID:40334203

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/40334203
DOI: 10.1371/journal.pgph.0004338
License (as archived): CC0-1.0
Archived: 2026-10-06T11:29:00.056Z
SHA-256 of the archived text: 9f4964c8374a75a9a13e3cbe9bac7a29c59a444c0833c6cf379d8f21558a6f81
Stable URL of this page: https://metraipolis.com/documento/dc_aaa55b437178

How to cite

A comparison of all-cause and HIV cause-specific mortality among children under 5 years of age before and during COVID-19 in Kenya, 2018-2022 — Europe PMC PMID:40334203 — Europe PMC (en), https://europepmc.org/article/MED/40334203 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_aaa55b437178 (Metraipolis archive dc_aaa55b437178, sha256 9f4964c8374a75a9a13e3cbe9bac7a29c59a444c0833c6cf379d8f21558a6f81)

BibTeX

@misc{dcaaa55b437178,
  title = {A comparison of all-cause and HIV cause-specific mortality among children under 5 years of age before and during COVID-19 in Kenya, 2018-2022 — Europe PMC PMID:40334203},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/40334203},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_aaa55b437178; sha256 9f4964c8374a75a9a13e3cbe9bac7a29c59a444c0833c6cf379d8f21558a6f81},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/40334203. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

The impact of the COVID-19 pandemic on pediatric mortality, including measures to ensure continuity of HIV care, is not well described in Kenya. We evaluated causes of death (COD) among decedents under 5 years of age both before and during the COVID-19 pandemic in Kenya. We analyzed Child Health and Mortality Prevention Surveillance (CHAMPS) data collected in February 2018-March 2022. We describe the proportional contribution of specific conditions in the causal chain of death among decedents aged 28 days to 59 months who underwent minimally invasive tissue (MITS) sampling, had an HIV polymerase chain reaction, and a COD determination. We also calculated all-cause and HIV cause-specific mortality rates using data from two health and demographic surveillance system (HDSS) sites in western Kenya. Results were stratified by time periods: February 2018 to February 2020, and March 2020 to March 2022. Among 269 MITS-eligible decedents, 55.8% died during the pre-COVID period. Of these, 53.7% were infants (28 days to 11 months), and 9.7% were HIV-positive. Leading causes of death for infants included malnutrition (20.5%), pneumonia (17.5%), sepsis (17.1%), and malaria (14.5%). For older children (12-59 months), the predominant causes were malaria (25.6%), malnutrition (21.1%), pneumonia (14.1%), and sepsis (13.1%). All-cause mortality rates did not differ significantly between the periods (53.9 vs. 52.8 per 1,000 live births, p=0.77), but HIV cause-specific mortality rates were significantly lower during March 2020-March 2022 compared to February 2018-February 2020 (1.2 vs. 3.1 per 1,000 live births, p=0.01). Malaria, malnutrition, pneumonia, and sepsis were the leading COD among decedents aged 28 days to 59 months enrolled in CHAMPS between February 2018 and March 2022. These findings may point to the need for urgent, focused efforts to prevent avoidable child deaths. Continued monitoring of HIV-related mortality could provide insights into the ongoing impact of the HIV program in the region.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: PLOS global public health, 2025 (prima pubblicazione 2025-05-07).
Identificativi: PMID 40334203 · PMCID PMC12058159 · DOI 10.1371/journal.pgph.0004338.
Pagina: https://europepmc.org/article/MED/40334203 — https://doi.org/10.1371/journal.pgph.0004338. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-10-06T09:52:29.930Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.