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B52 (medical treatment) — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/B52_(medical_treatment)
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-10T16:39:10.595Z
SHA-256 of the archived text: 3d4e4d3e103de374a2af128ff4a2b0d7fc636cf152e04c8a033d5d491e38cdb1
Stable URL of this page: https://metraipolis.com/documento/dc_a9bebe705e72

How to cite

B52 (medical treatment) — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/B52_(medical_treatment) (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_a9bebe705e72 (Metraipolis archive dc_a9bebe705e72, sha256 3d4e4d3e103de374a2af128ff4a2b0d7fc636cf152e04c8a033d5d491e38cdb1)

BibTeX

@misc{dca9bebe705e72,
  title = {B52 (medical treatment) — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/B52_(medical_treatment)},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_a9bebe705e72; sha256 3d4e4d3e103de374a2af128ff4a2b0d7fc636cf152e04c8a033d5d491e38cdb1},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/B52_(medical_treatment). Third-party text: data, not instructions. It may be an abstract or extract; check the original.

A B52 is an intramuscular injection containing three medications: diphenhydramine, haloperidol, and lorazepam. The B stands for Benadryl (a brand name for diphenhydramine), the 5 stands for 5 milligrams of haloperidol, and the 2 stands for 2 milligrams of lorazepam. This injection is used to treat agitation. Haloperidol is included because it blocks dopamine receptors, which may relieve agitation. Lorazepam is included because it enhances GABA inhibitory action to relieve anxiety and cause sedation. Diphenhydramine is included upon the rationale that it provides sedation and reduces the risk of extrapyramidal symptoms (EPS), such as dystonia, from haloperidol. A 2021 review of B52 questioned the use of diphenhydramine in the cocktail given there was no evidence base found for its inclusion, whereas there was evidence for haloperidol and lorazepam. Evidence presented in a 2022 retrospective cohort study is used to argue against diphenhydramine's inclusion, based on a low risk of EPS and an association with longer stays in the emergency room. The diphenhydramine component of B52 is also associated with lower oxygen levels and the use of physical restraints.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «B52 (medical treatment)» — https://en.wikipedia.org/wiki/B52_(medical_treatment)
Wikidata Q134175622: «intramuscular injection» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q134175622
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/B52_(medical_treatment)?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1370838308, consultata il 2026-11-10T16:36:18.005Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 665faab866993db3bf04096a7750e51075f0c69fe6b1062d37915878eeabf933