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Argatroban — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Argatroban
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-09T20:36:45.527Z
SHA-256 of the archived text: 6a69986fd0af1485cd26445fc6ef811fc8ce62831cbec1f2abebc0f12532f885
Stable URL of this page: https://metraipolis.com/documento/dc_996c19d6ad8a

How to cite

Argatroban — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Argatroban (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_996c19d6ad8a (Metraipolis archive dc_996c19d6ad8a, sha256 6a69986fd0af1485cd26445fc6ef811fc8ce62831cbec1f2abebc0f12532f885)

BibTeX

@misc{dc996c19d6ad8a,
  title = {Argatroban — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Argatroban},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_996c19d6ad8a; sha256 6a69986fd0af1485cd26445fc6ef811fc8ce62831cbec1f2abebc0f12532f885},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Argatroban. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. In 2000, argatroban was licensed by the US Food and Drug Administration (FDA) for prophylaxis or treatment of thrombosis in people with heparin-induced thrombocytopenia (HIT). In 2002, it was approved for use during percutaneous coronary interventions in people who have HIT or are at risk for developing it. In 2012, it was approved by the UK Medicines and Healthcare products Regulatory Agency for anticoagulation in people with heparin-induced thrombocytopenia Type II (HIT) who require parenteral antithrombotic therapy. Argatroban is given intravenously and drug plasma concentrations reach steady state in 1–3 hours. Argatroban is metabolized in the liver and has a half-life of about 50 minutes. It is monitored by PTT. Because of its hepatic metabolism, it may be used in patients with renal dysfunction. (This is in contrast to lepirudin, a direct thrombin inhibitor that is primarily renally cleared).

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «Argatroban» — https://en.wikipedia.org/wiki/Argatroban
Wikidata Q474880: «composto chimico» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q474880
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Argatroban?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1329241737, consultata il 2026-11-09T20:33:19.678Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: a165c857f4dd15133d920cb1e9e25c72dac05761347cce7f50e1f882dc59ad29