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Aplaviroc — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Aplaviroc
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-09T16:51:54.088Z
SHA-256 of the archived text: 5c3f2dea84e6e7a5c018f53556a6450d2b542bd1e6ae3f54020f25cd35ee77b7
Stable URL of this page: https://metraipolis.com/documento/dc_8bb9ca8d759d

How to cite

Aplaviroc — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Aplaviroc (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_8bb9ca8d759d (Metraipolis archive dc_8bb9ca8d759d, sha256 5c3f2dea84e6e7a5c018f53556a6450d2b542bd1e6ae3f54020f25cd35ee77b7)

BibTeX

@misc{dc8bb9ca8d759d,
  title = {Aplaviroc — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Aplaviroc},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_8bb9ca8d759d; sha256 5c3f2dea84e6e7a5c018f53556a6450d2b542bd1e6ae3f54020f25cd35ee77b7},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Aplaviroc. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Aplaviroc (INN, codenamed AK602 and GSK-873140) is a CCR5 entry inhibitor that belongs to a class of 2,5-diketopiperazines developed for the treatment of HIV infection. It was developed by GlaxoSmithKline. In October 2005, all studies of aplaviroc were discontinued due to liver toxicity concerns. Some authors have claimed that evidence of poor efficacy may have contributed to termination of the drug's development; the ASCENT study, one of the discontinued trials, showed aplaviroc to be under-effective in many patients even at high concentrations.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «Aplaviroc» — https://en.wikipedia.org/wiki/Aplaviroc
Wikidata Q4779956: «composto chimico» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q4779956
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Aplaviroc?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1346905326, consultata il 2026-11-09T16:48:34.443Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: fd9fadfa777767d8ac4f7e59c21fd9682b91971cb1a12bd601916752b92198d5