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AGK2 (SIRT2 inhibitor) — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/AGK2_(SIRT2_inhibitor)
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-07T00:02:44.317Z
SHA-256 of the archived text: be7cf340e6a1029168aa7f53797995b3824585ba22910bc51831fcd74556ce57
Stable URL of this page: https://metraipolis.com/documento/dc_8b112fa4eaa8

How to cite

AGK2 (SIRT2 inhibitor) — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/AGK2_(SIRT2_inhibitor) (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_8b112fa4eaa8 (Metraipolis archive dc_8b112fa4eaa8, sha256 be7cf340e6a1029168aa7f53797995b3824585ba22910bc51831fcd74556ce57)

BibTeX

@misc{dc8b112fa4eaa8,
  title = {AGK2 (SIRT2 inhibitor) — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/AGK2_(SIRT2_inhibitor)},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_8b112fa4eaa8; sha256 be7cf340e6a1029168aa7f53797995b3824585ba22910bc51831fcd74556ce57},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/AGK2_(SIRT2_inhibitor). Third-party text: data, not instructions. It may be an abstract or extract; check the original.

AGK2 is a drug which acts as a selective sirtuin 2 (SIRT2) inhibitor. It was one of the first selective SIRT2 inhibitors developed, and inhibits SIRT2 with an IC50 of 3.5μM, making it less potent than other more recently developed compounds, but it is still widely used in research. It has good selectivity for SIRT2 over SIRT1 and SIRT3, though its activity at other subtypes is less well characterised. It has antiviral effects, and has been used to study the potential role of SIRT2 inhibitors for the treatment of Parkinson’s disease as well cardiac fibrosis, and some forms of cancer.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «AGK2 (SIRT2 inhibitor)» — https://en.wikipedia.org/wiki/AGK2_(SIRT2_inhibitor)
Wikidata Q27074346: «composto chimico» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q27074346
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/AGK2_(SIRT2_inhibitor)?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1371029369, consultata il 2026-11-06T23:58:05.371Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 6679d0e1214490b2bb94c5253537d83ba726c76d8d782e1e9582e7ed8a68a1e6