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Cumulative Human Health Risk Assessment of Regional Ozone and Volatile Organic Compounds from Unconventional Oil and Gas Sites in Colorado's Front Range — Europe PMC PMID:40305737

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/40305737
DOI: 10.1289/ehp16272
License (as archived): CC0-1.0
Archived: 2026-10-06T10:16:04.281Z
SHA-256 of the archived text: bfb6bfbfcfce1ea5b726b2487d0da6ceaae6d7fc2f08ae1b6947be251754f98f
Stable URL of this page: https://metraipolis.com/documento/dc_8a13cb8a2fde

How to cite

Cumulative Human Health Risk Assessment of Regional Ozone and Volatile Organic Compounds from Unconventional Oil and Gas Sites in Colorado's Front Range — Europe PMC PMID:40305737 — Europe PMC (en), https://europepmc.org/article/MED/40305737 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_8a13cb8a2fde (Metraipolis archive dc_8a13cb8a2fde, sha256 bfb6bfbfcfce1ea5b726b2487d0da6ceaae6d7fc2f08ae1b6947be251754f98f)

BibTeX

@misc{dc8a13cb8a2fde,
  title = {Cumulative Human Health Risk Assessment of Regional Ozone and Volatile Organic Compounds from Unconventional Oil and Gas Sites in Colorado's Front Range — Europe PMC PMID:40305737},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/40305737},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_8a13cb8a2fde; sha256 bfb6bfbfcfce1ea5b726b2487d0da6ceaae6d7fc2f08ae1b6947be251754f98f},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/40305737. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Background: Most unconventional oil and gas (UOG) extraction in Colorado occurs within the Denver Metro/North Front Range (DMNFR) ozone Nonattainment Area (NAA). Previous UOG human health risk assessments do not consider cumulative risk from both volatile organic compounds (VOCs) and criteria air pollutants like ozone. Methods: We conducted a cumulative human health risk assessment (CHHRA) using regulatory-grade 1- and 8-h ozone measurements from a DMNFR US Environmental Protection Agency (US EPA) monitoring station and weekly and short-term (15 s-1 min) VOC air quality monitoring data collected between 2018-2023 from 10 near-pad air monitoring sites, three community sites, and one background site. Acute and chronic noncancer hazard indices (HIs) for multiple health end points, as well as cancer risks, were calculated during well drilling, well completions, and production activity periods and compared between sites. VOC concentrations were compared between operations that used a petroleum-based drilling fluid vs. a synthetic drill fluid. Differences in weekly chemical concentrations between sites, UOG phases, and drill muds were analyzed using repeated measures analysis of variance with post hoc pairwise comparisons with Bonferroni adjustment. Results: Acute HIs of VOCs and ozone ranged from 1.34×10-4 to 31.33 at the 95th percentile concentrations at all sites. One of the three community monitoring sites, Anthem, exceeded US EPA thresholds for respiratory, immunological, and developmental end points during production and for the immunological end point during well completions. At the near-pad sites, acute hazards exceeded US EPA thresholds during well completions for immunological, respiratory, reproductive, developmental, and neurological end points. Neurological and immunological HIs were above thresholds for the drilling phase at near-pad sites. Chronic HIs ranged from 8.43×10-4 to 0.47 at 95th percentile concentrations and, therefore, were below the HI threshold for all near-pad and community sites for all health end points. Cancer risks ranging from 209 to 335 in a million at 95th percentile concentrations were above US EPA thresholds for all sites, including the background site, which is more heavily influenced by Denver Metro traffic emissions. Conclusions: Our results suggest that for communities located near UOG well pads in the DMNFR ozone NAA, acute health risks persist after the implementation of best management practices to reduce emissions. Greater protection to public health could be afforded by establishing policies that require drilling and well completions to be conducted outside the summer ozone season. Further research is needed to address potential health risks from the use of synthetic drilling fluid. https://doi.org/10.1289/EHP16272.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: Environmental health perspectives, 2025 (prima pubblicazione 2025-05-28).
Identificativi: PMID 40305737 · PMCID PMC12120841 · DOI 10.1289/ehp16272.
Descrittori MeSH principali: Ozone; Air Pollutants; Environmental Exposure; Volatile Organic Compounds; Oil and Gas Fields.
Pagina: https://europepmc.org/article/MED/40305737 — https://doi.org/10.1289/ehp16272. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-10-06T09:45:27.550Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.