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C-C chemokine receptor type 7 — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/C-C_chemokine_receptor_type_7
License (as archived): CC-BY-SA-4.0
Archived: 2026-10-31T09:14:50.064Z
SHA-256 of the archived text: 69ef04f3c97a91e50cc041e542d9a3ef233f80a37855b333fd46fb575f3ee468
Stable URL of this page: https://metraipolis.com/documento/dc_882fc4fcfd43

How to cite

C-C chemokine receptor type 7 — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/C-C_chemokine_receptor_type_7 (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_882fc4fcfd43 (Metraipolis archive dc_882fc4fcfd43, sha256 69ef04f3c97a91e50cc041e542d9a3ef233f80a37855b333fd46fb575f3ee468)

BibTeX

@misc{dc882fc4fcfd43,
  title = {C-C chemokine receptor type 7 — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/C-C_chemokine_receptor_type_7},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_882fc4fcfd43; sha256 69ef04f3c97a91e50cc041e542d9a3ef233f80a37855b333fd46fb575f3ee468},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/C-C_chemokine_receptor_type_7. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. Two ligands have been identified for this receptor: the chemokine (C-C motif) ligand 19 (CCL19/ELC) and (C-C motif) ligand 21 (CCL21). The ligands have similar affinity for the receptor, though CCL19 has been shown to induce internalisation of CCR7 and desensitisation of the cell to CCL19/CCL21 signals. CCR7 is a transmembrane protein with seven transmembrane domains, which is coupled with heterotrimeric G proteins, which transduce the signal downstream through various signalling cascades. The main function of the receptor is to guide immune cells to immune organs (lymph nodes, thymus, spleen) by detecting specific chemokines, which these tissues secrete. CCR7 has also recently been designated CD197 (cluster of differentiation 197).

Tema degli esploratori: scienze della vita e salute (deposito sistematico; ricerca «immunology»).
Fonte: Wikipedia in inglese, voce «C-C chemokine receptor type 7» — https://en.wikipedia.org/wiki/C-C_chemokine_receptor_type_7
Wikidata Q17907809: «proteina» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q17907809
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/C-C_chemokine_receptor_type_7?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1377962752, consultata il 2026-10-31T09:03:27.700Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 0e8be531e88d98547b6c80c28ad32cdc5a7489a4067c6c3b719a2a956db6788f