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Development of a multi-year white-nose syndrome mitigation strategy using antifungal volatile organic compounds — Europe PMC PMID:36454924

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/36454924
DOI: 10.1371/journal.pone.0278603
License (as archived): CC0-1.0
Archived: 2026-10-10T02:58:11.825Z
SHA-256 of the archived text: 1d41ebe857d40b382affcdd571d811dff84667817b79806a014788ee0f7f55b0
Stable URL of this page: https://metraipolis.com/documento/dc_8769deffdb99

How to cite

Development of a multi-year white-nose syndrome mitigation strategy using antifungal volatile organic compounds — Europe PMC PMID:36454924 — Europe PMC (en), https://europepmc.org/article/MED/36454924 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_8769deffdb99 (Metraipolis archive dc_8769deffdb99, sha256 1d41ebe857d40b382affcdd571d811dff84667817b79806a014788ee0f7f55b0)

BibTeX

@misc{dc8769deffdb99,
  title = {Development of a multi-year white-nose syndrome mitigation strategy using antifungal volatile organic compounds — Europe PMC PMID:36454924},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/36454924},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_8769deffdb99; sha256 1d41ebe857d40b382affcdd571d811dff84667817b79806a014788ee0f7f55b0},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/36454924. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Pseudogymnoascus destructans is a fungal pathogen responsible for a deadly disease among North American bats known as white-nose syndrome (WNS). Since detection of WNS in the United States in 2006, its rapid spread and high mortality has challenged development of treatment and prevention methods, a significant objective for wildlife management agencies. In an effort to mitigate precipitous declines in bat populations due to WNS, we have developed and implemented a multi-year mitigation strategy at Black Diamond Tunnel (BDT), Georgia, singly known as one of the most substantial winter colony sites for tricolored bats (Perimyotis subflavus), with pre-WNS abundance exceeding 5000 individuals. Our mitigation approach involved in situ treatment of bats at the colony level through aerosol distribution of antifungal volatile organic compounds (VOCs) that demonstrated an in vitro ability to inhibit P. destructans conidia germination and mycelial growth through contact-independent exposure. The VOCs evaluated have been identified from microbes inhabiting naturally-occurring fungistatic soils and endophytic fungi. These VOCs are of low toxicity to mammals and have been observed to elicit antagonism of P. destructans at low gaseous concentrations. Cumulatively, our observations resolved no detrimental impact on bat behavior or health, yet indicated a potential for attenuation of WNS related declines at BDT and demonstrated the feasibility of this novel disease management approach.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: PloS one, 2022 (prima pubblicazione 2022-12-01).
Identificativi: PMID 36454924 · PMCID PMC9714803 · DOI 10.1371/journal.pone.0278603.
Descrittori MeSH principali: Chiroptera; Volatile Organic Compounds.
Pagina: https://europepmc.org/article/MED/36454924 — https://doi.org/10.1371/journal.pone.0278603. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-10-10T02:37:36.867Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.