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4-Hydroxynonenal — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/4-Hydroxynonenal
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-06T15:51:23.752Z
SHA-256 of the archived text: 2359f53ec69c098ec3c1ebff7e1ae63a37ed22720be6b1c05806568d69cc02fa
Stable URL of this page: https://metraipolis.com/documento/dc_80ce99ddec0a

How to cite

4-Hydroxynonenal — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/4-Hydroxynonenal (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_80ce99ddec0a (Metraipolis archive dc_80ce99ddec0a, sha256 2359f53ec69c098ec3c1ebff7e1ae63a37ed22720be6b1c05806568d69cc02fa)

BibTeX

@misc{dc80ce99ddec0a,
  title = {4-Hydroxynonenal — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/4-Hydroxynonenal},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_80ce99ddec0a; sha256 2359f53ec69c098ec3c1ebff7e1ae63a37ed22720be6b1c05806568d69cc02fa},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/4-Hydroxynonenal. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

4-Hydroxynonenal, or 4-hydroxy-2E-nonenal or 4-hydroxy-2-nonenal or 4-HNE or HNE, (C9H16O2), is an α,β-unsaturated hydroxyalkenal that is produced by lipid peroxidation in cells. 4-HNE is the primary α,β-unsaturated hydroxyalkenal formed in this process. It is a colorless oil. It is found throughout animal tissues, and in higher quantities during oxidative stress due to the increase in the lipid peroxidation chain reaction, due to the increase in stress events. 4-HNE has been hypothesized to play a key role in cell signal transduction, in a variety of pathways from cell cycle events to cellular adhesion. Early identification and characterization of 4-hydroxynonenal was reported by Esterbauer, et al., who also obtained the same compound synthetically. The topic has since been often reviewed, and one source describes the compound as "the most studied LPO (lipid peroxidation) product with pleiotropic capabilities".

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «4-Hydroxynonenal» — https://en.wikipedia.org/wiki/4-Hydroxynonenal
Wikidata Q229982: «composto chimico» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q229982
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/4-Hydroxynonenal?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1331280981, consultata il 2026-11-06T15:42:27.985Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 848ab13a1087554fc4d9c146bf1b15d48f73b706d48a8884f4b517c5a692145d