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5-Methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/5-Methyltetrahydrofolate:corrinoid/iron-sulfur_protein_Co-methyltransferase
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-06T17:33:00.045Z
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5-Methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/5-Methyltetrahydrofolate:corrinoid/iron-sulfur_protein_Co-methyltransferase (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_7fa8a3de1070 (Metraipolis archive dc_7fa8a3de1070, sha256 75a6fac50e49fbeac792349f5c07d5bb80d3cc9f27a6d532d273ce5dedf36950)

BibTeX

@misc{dc7fa8a3de1070,
  title = {5-Methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/5-Methyltetrahydrofolate:corrinoid/iron-sulfur_protein_Co-methyltransferase},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_7fa8a3de1070; sha256 75a6fac50e49fbeac792349f5c07d5bb80d3cc9f27a6d532d273ce5dedf36950},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/5-Methyltetrahydrofolate:corrinoid/iron-sulfur_protein_Co-methyltransferase. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase (EC 2.1.1.258, acsE (gene)) is an enzyme with systematic name 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase. This enzyme catalyses the following chemical reaction [Methyl-Co(III) corrinoid Fe-S protein] + tetrahydrofolate ⇌ {\displaystyle \rightleftharpoons } a [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrofolate This enzyme catalyses the transfer of a carbon atom and associated hydrogen atoms from the N5 position of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein, containing a corrin ring similar to that in cobalamin. Although called a methyl transferase, the net transfer is of one carbon atom and two hydrogen atoms – the methyltetrahydrofolate contains only two hydrogen atoms more than the tetrahydrofolate. The cobalt atom is able to change oxidation state by obtaining electrons from the 4Fe-4S complex in the protein.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «5-Methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase» — https://en.wikipedia.org/wiki/5-Methyltetrahydrofolate:corrinoid/iron-sulfur_protein_Co-methyltransferase
Wikidata Q5155820: «class of enzymes» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q5155820
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/5-Methyltetrahydrofolate:corrinoid/iron-sulfur_protein_Co-methyltransferase?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1278071506, consultata il 2026-11-06T17:25:22.521Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 6bf9ab2c152374955722c4ac4817d3580d3136b62ab062a303827f1722690738