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Implementation of basic package of care improved socio-economic conditions of lymphedema patients in rural Mali after two years follow-up — Europe PMC PMID:41218023

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/41218023
DOI: 10.1371/journal.pgph.0005454
License (as archived): CC0-1.0
Archived: 2026-10-06T08:50:37.067Z
SHA-256 of the archived text: 80eb9d9167752781f43bf9afb62ac4ededddddc89a7d97c81ecc195f96b1ea1a
Stable URL of this page: https://metraipolis.com/documento/dc_7ae44c224bbf

How to cite

Implementation of basic package of care improved socio-economic conditions of lymphedema patients in rural Mali after two years follow-up — Europe PMC PMID:41218023 — Europe PMC (en), https://europepmc.org/article/MED/41218023 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_7ae44c224bbf (Metraipolis archive dc_7ae44c224bbf, sha256 80eb9d9167752781f43bf9afb62ac4ededddddc89a7d97c81ecc195f96b1ea1a)

BibTeX

@misc{dc7ae44c224bbf,
  title = {Implementation of basic package of care improved socio-economic conditions of lymphedema patients in rural Mali after two years follow-up — Europe PMC PMID:41218023},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/41218023},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_7ae44c224bbf; sha256 80eb9d9167752781f43bf9afb62ac4ededddddc89a7d97c81ecc195f96b1ea1a},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/41218023. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Research shows that a local hygiene package washing, wound care, and exercise improves lymphedema (LE) patients' quality of life by reducing ADLA, costs, stigma, and boosting work capacity. The 'LEdoxy' study, a 24-month, multicountry, double-blind, randomized controlled trial of doxycycline plus hygiene, investigated the efficacy of daily doxycycline versus a placebo for lymphatic filariasis in Mali, India, and Sri Lanka. All 'LEdoxy' participants consistently followed a standardized hygiene program. This study, embedded within the previous 'LEdoxy' study, assessed cost reductions in ADLA management and evaluated the social impact of the regular local care based on the HP among LE patients in Mali. We conducted a cross-sectional study embedded in "LEdoxy" study participants in the health districts of Kolondieba and Kolokani from September to December 2021. Questionnaire was used to collect retrospective data on pre-trial conditions and prospective data on post-trial conditions. Data were collected using a digital questionnaire and qualitative methods, including in-depth interviews and focus group discussions with interview guide, without recycling 'LEDoxy' data. These quantitative data were analysed using SPSS version 25.0. We performed a thematic analysis approach using Quirkos version 2. We investigated 196 LE patients with a median age of 56 years [range: 25-70 years]. We observed a reduction in the monthly frequency of acute ADLA from 90.8% (178/196) before the trial to 43.9%, (86/196) after the trial (p<0.05). Importantly, in term of economic evaluation the average ADLA attack management cost decreased significantly from US$20.01(± US $18.56) before the trial to US$5.7(± US $4.78), after the trial (p< 0.001). Patients reported that the hygiene program reduced social isolation and stigma and improved their ability to work. Using a basic care package improved LE patients' quality of life by lowering ADLA costs. To sustain this, community-based programs that include income-generating activities are essential.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: PLOS global public health, 2025 (prima pubblicazione 2025-11-11).
Identificativi: PMID 41218023 · PMCID PMC12604757 · DOI 10.1371/journal.pgph.0005454.
Pagina: https://europepmc.org/article/MED/41218023 — https://doi.org/10.1371/journal.pgph.0005454. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-10-06T08:20:26.649Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.