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Synaptic tagging — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Synaptic_tagging
License (as archived): CC-BY-SA-4.0
Archived: 2026-10-07T19:02:38.443Z
SHA-256 of the archived text: f4f749bc9a3a1c2c89dca9926ae4a3c80a0809341cdcc8606a7e918e9061a709
Stable URL of this page: https://metraipolis.com/documento/dc_78ef170fcf4e

How to cite

Synaptic tagging — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Synaptic_tagging (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_78ef170fcf4e (Metraipolis archive dc_78ef170fcf4e, sha256 f4f749bc9a3a1c2c89dca9926ae4a3c80a0809341cdcc8606a7e918e9061a709)

BibTeX

@misc{dc78ef170fcf4e,
  title = {Synaptic tagging — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Synaptic_tagging},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_78ef170fcf4e; sha256 f4f749bc9a3a1c2c89dca9926ae4a3c80a0809341cdcc8606a7e918e9061a709},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Synaptic_tagging. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Synaptic tagging, or the synaptic tagging hypothesis, has been proposed to explain how neural signaling at a particular synapse creates a target for subsequent plasticity-related product (PRP) trafficking essential for sustained LTP and LTD. Although the molecular identity of the tags remains unknown, it has been established that they form as a result of high or low frequency stimulation, interact with incoming PRPs, and have a limited lifespan. Further investigations have suggested that plasticity-related products include mRNA and proteins from both the soma and dendritic shaft that must be captured by molecules within the dendritic spine to achieve persistent LTP and LTD. This idea was articulated in the synaptic tag-and-capture hypothesis. Overall, synaptic tagging elaborates on the molecular underpinnings of how L-LTP is generated and leads to memory formation.

Tema degli esploratori: scienze della vita e salute (deposito sistematico; categoria «Neuroscience»).
Fonte: Wikipedia in inglese, voce «Synaptic tagging» — https://en.wikipedia.org/wiki/Synaptic_tagging
Wikidata Q7662042 (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q7662042
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Synaptic_tagging?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1327040456, consultata il 2026-10-07T18:25:37.045Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 90201c14b9041d43bf9bf6a5949da8665747102c9f2894e0511a6a8e0f6b4d3c