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Aspergillopepsin II — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Aspergillopepsin_II
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-10T04:13:16.913Z
SHA-256 of the archived text: 9d4acfceecc049668c4deeeb8e36e2e94c4440f1625a3e26a5edaa887a646d57
Stable URL of this page: https://metraipolis.com/documento/dc_75cdfdddd513

How to cite

Aspergillopepsin II — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Aspergillopepsin_II (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_75cdfdddd513 (Metraipolis archive dc_75cdfdddd513, sha256 9d4acfceecc049668c4deeeb8e36e2e94c4440f1625a3e26a5edaa887a646d57)

BibTeX

@misc{dc75cdfdddd513,
  title = {Aspergillopepsin II — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Aspergillopepsin_II},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_75cdfdddd513; sha256 9d4acfceecc049668c4deeeb8e36e2e94c4440f1625a3e26a5edaa887a646d57},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Aspergillopepsin_II. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Aspergilloglutamic peptidase, also called aspergillopepsin II (EC 3.4.23.19, proctase A, Aspergillus niger acid proteinase A, Aspergillus niger var. macrosporus aspartic proteinase) is a proteolytic enzyme. The enzyme was previously thought be an aspartic protease, but it was later shown to be a glutamic protease with a catalytic Glu residue at the active site, and was therefore renamed aspergilloglutamic peptidase. Determination of its molecular structure showed it to be a unique two-chain enzyme with a light chain and a heavy chain bound non-covalently with each other. The C-terminal region of the light chain of one molecule binds to the active site cleft of another molecule in the manner of a substrate. This enzyme catalyses the following chemical reaction Preferential cleavage in B chain of insulin: Asn3-Gln, Gly13-Ala, Tyr26-Thr This enzyme is isolated from Aspergillus niger var. macrosporus.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «Aspergillopepsin II» — https://en.wikipedia.org/wiki/Aspergillopepsin_II
Wikidata Q12903307 (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q12903307
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Aspergillopepsin_II?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1306542093, consultata il 2026-11-10T04:11:03.248Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 5477117bcf5d333ac47868e4b874aa844c30c5bd1ab0ad384d0971a722d0044c