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Identification of risk factors and mosquito vectors associated with dengue virus infection in American Samoa, 2017 — Europe PMC PMID:37418355

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/37418355
DOI: 10.1371/journal.pgph.0001604
License (as archived): CC0-1.0
Archived: 2026-10-07T12:58:04.570Z
SHA-256 of the archived text: 5687fbb5c20021e5838e484a4d240e981a8ee4e818d526ec9c14bdef5b481ff2
Stable URL of this page: https://metraipolis.com/documento/dc_7259e07bf71e

How to cite

Identification of risk factors and mosquito vectors associated with dengue virus infection in American Samoa, 2017 — Europe PMC PMID:37418355 — Europe PMC (en), https://europepmc.org/article/MED/37418355 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_7259e07bf71e (Metraipolis archive dc_7259e07bf71e, sha256 5687fbb5c20021e5838e484a4d240e981a8ee4e818d526ec9c14bdef5b481ff2)

BibTeX

@misc{dc7259e07bf71e,
  title = {Identification of risk factors and mosquito vectors associated with dengue virus infection in American Samoa, 2017 — Europe PMC PMID:37418355},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/37418355},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_7259e07bf71e; sha256 5687fbb5c20021e5838e484a4d240e981a8ee4e818d526ec9c14bdef5b481ff2},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/37418355. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Introduction: The first outbreak of dengue in American Samoa was reported in 1911. Sporadic outbreaks have been reported since, as were outbreaks of other pathogens transmitted by Aedes species mosquitoes including Ross River, chikungunya, and Zika viruses. During an outbreak of dengue virus-type 2 (DENV-2) in 2016-2018, we conducted household-based cluster investigations to identify population-specific risk factors associated with infection and performed entomologic surveillance to determine the relative abundance of Ae. aegypti and Ae. polynesiensis. Methods and findings: We contacted dengue patients who had tested positive for DENV infection and offered them as well as their household members participation in household-based cluster investigations. For those that accepted participation, we also offered participation to residents of households within a 50-meter radius of each case-patient's home. Questionnaires were administered and serum specimens collected for testing by RT-PCR and anti-DENV IgM ELISA. Adult female mosquitoes were aspirated from inside and outside participating households and tested by RT-PCR. We analyzed characteristics associated with DENV infection in bivariate analyses. A total of 226 participants was enrolled from 91 households in 20 clusters. Median age of participants was 34 years (range: <1-94), and 56.2% were female. In total, 7 (3.2%) participants had evidence of DENV infection by IgM ELISA (n = 5) or RT-PCR (n = 2). Factors significantly associated with DENV infection were reporting a febrile illness in the past three months (prevalence ratio: 7.5 [95% confidence interval: 1.9-29.8]) and having a household septic tank (Fisher's Exact Test, p = 0.004). Of 93 Ae. aegypti and 90 Ae. polynesiensis females collected, 90% of Ae. aegypti were collected inside homes whereas 83% of Ae. polynesiensis were collected outside homes. DENV nucleic acid was not detected in any mosquito pools. Sequencing of the DENV-2 from patient specimens identified the Cosmopolitan genotype of DENV-2 and was most closely related to virus detected in the Solomon Islands during 2016. Conclusions: This investigation demonstrated that dengue is a continuing risk in American Samoa. Increased frequency of infection among residents with a septic tank suggests a need to investigate whether septic tanks serve as larval habitats for mosquito vectors of DENV in American Samoa. Future efforts should also evaluate the role of Ae. polynesiensis in DENV transmission in the wild.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: PLOS global public health, 2023 (prima pubblicazione 2023-07-07).
Identificativi: PMID 37418355 · PMCID PMC10328243 · DOI 10.1371/journal.pgph.0001604.
Pagina: https://europepmc.org/article/MED/37418355 — https://doi.org/10.1371/journal.pgph.0001604. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-10-07T12:28:09.669Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.