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Atrial natriuretic peptide — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Atrial_natriuretic_peptide
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-10T07:33:23.060Z
SHA-256 of the archived text: 1cefc7d1358158c8968722988fb3b22a88baa976b78a9b4db11577fac058b9a4
Stable URL of this page: https://metraipolis.com/documento/dc_70bdfb320232

How to cite

Atrial natriuretic peptide — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Atrial_natriuretic_peptide (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_70bdfb320232 (Metraipolis archive dc_70bdfb320232, sha256 1cefc7d1358158c8968722988fb3b22a88baa976b78a9b4db11577fac058b9a4)

BibTeX

@misc{dc70bdfb320232,
  title = {Atrial natriuretic peptide — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Atrial_natriuretic_peptide},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_70bdfb320232; sha256 1cefc7d1358158c8968722988fb3b22a88baa976b78a9b4db11577fac058b9a4},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Atrial_natriuretic_peptide. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Atrial natriuretic peptide (natriuretic polypeptide (ANP) or atrial natriuretic factor (ANF) is a natriuretic peptide hormone secreted from the cardiac atria that in humans is encoded by the NPPA gene. Natriuretic peptides (ANP, BNP, and CNP) are a family of hormone/paracrine factors that are structurally related. The main function of ANP is causing a reduction in expanded extracellular fluid (ECF) volume by increasing renal sodium excretion. ANP is synthesized and secreted by cardiac muscle cells in the walls of the atria in the heart. These cells contain volume receptors which respond to increased stretching of the atrial wall due to increased atrial blood volume. Reduction of blood volume by ANP can result in secondary effects such as reduction of extracellular fluid (ECF) volume, improved cardiac ejection fraction with resultant improved organ perfusion, decreased blood pressure, and increased serum potassium. These effects may be blunted or negated by various counter-regulatory mechanisms operating concurrently on each of these secondary effects. Brain natriuretic peptide (BNP) – a misnomer; it is secreted by cardiac muscle cells in the heart ventricles – is similar to ANP in its effect. It acts via the same receptors as ANP does, but with 10-fold lower affinity than ANP. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better choices than ANP for diagnostic blood testing.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «Atrial natriuretic peptide» — https://en.wikipedia.org/wiki/Atrial_natriuretic_peptide
Wikidata Q78185357: «Ormone di origine peptidica prodotto da cellule specializzate del miocardio. È conosciuto anche come fattore natriuretico atriale (ANF), ormone natriuretico atriale (ANH) e atriopeptina.» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q78185357
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Atrial_natriuretic_peptide?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1377740543, consultata il 2026-11-10T07:29:32.422Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 779b8e1d6145068c5fd59fcab005f620d0d7691438c94b3eb99982a0e1b92f28