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Information Hyperlinked over Proteins — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Information_Hyperlinked_over_Proteins
License (as archived): CC-BY-SA-4.0
Archived: 2026-10-07T19:04:48.367Z
SHA-256 of the archived text: 8ba5493f83c52d1d4ce36191918aea58a54d0e5c85f6b23e2741bddf88ab619b
Stable URL of this page: https://metraipolis.com/documento/dc_68138fe548fe

How to cite

Information Hyperlinked over Proteins — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Information_Hyperlinked_over_Proteins (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_68138fe548fe (Metraipolis archive dc_68138fe548fe, sha256 8ba5493f83c52d1d4ce36191918aea58a54d0e5c85f6b23e2741bddf88ab619b)

BibTeX

@misc{dc68138fe548fe,
  title = {Information Hyperlinked over Proteins — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Information_Hyperlinked_over_Proteins},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_68138fe548fe; sha256 8ba5493f83c52d1d4ce36191918aea58a54d0e5c85f6b23e2741bddf88ab619b},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Information_Hyperlinked_over_Proteins. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Information Hyperlinked over Proteins (or iHOP) is an online text mining service that provides a gene-guided network to access PubMed abstracts. The service was established by Robert Hoffmann and Alfonso Valencia in 2004. The concept underlying iHOP is that by using genes and proteins as hyperlinks between sentences and abstracts, the information in PubMed can be converted into one navigable resource. Navigating across interrelated sentences within this network rather than the use of conventional keyword searches allows for stepwise and controlled acquisition of information. Moreover, this literature network can be superimposed upon experimental interaction data to facilitate the simultaneous analysis of novel and existing knowledge. As of September 2014, the network presented in iHOP contains 28.4 million sentences and 110,000 genes from over 2,700 organisms, including the model organisms Homo sapiens, Mus musculus, Drosophila melanogaster, Caenorhabditis elegans, Danio rerio, Arabidopsis thaliana, Saccharomyces cerevisiae and Escherichia coli. The iHOP system has shown that by navigating from gene to gene, distant medical and biological concepts may be connected by only a small number of genes; the shortest path between two genes has been shown to involve on average four intermediary genes. The iHOP system architecture consists of two separate parts: the 'iHOP factory' and the web application. The iHOP factory manages the PubMed source data (text and gene data) and organises it within a PostgreSQL relational database. The iHOP factory also produces the relevant XML output for display by the web application. iHOP is free to use and is licensed under a Creative Commons BY-ND license.

Tema degli esploratori: scienze della vita e salute (deposito sistematico; categoria «Bioinformatics»).
Fonte: Wikipedia in inglese, voce «Information Hyperlinked over Proteins» — https://en.wikipedia.org/wiki/Information_Hyperlinked_over_Proteins
Wikidata Q168546 (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q168546
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Information_Hyperlinked_over_Proteins?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 965464722, consultata il 2026-10-07T18:28:13.012Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 0833aaa69d732ed502d760aa523a685b0c34711422d3f7eaec250ac79390c575