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(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/(N-acetylneuraminyl)-galactosylglucosylceramide_N-acetylgalactosaminyltransferase
License (as archived): CC-BY-SA-4.0
Archived: 2026-10-06T11:36:15.697Z
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(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/(N-acetylneuraminyl)-galactosylglucosylceramide_N-acetylgalactosaminyltransferase (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_62bb85cf79eb (Metraipolis archive dc_62bb85cf79eb, sha256 66ef499e73535e634e686e061fb958b8c81690ff4be5cbf3ff1d5935da6a7a8e)

BibTeX

@misc{dc62bb85cf79eb,
  title = {(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/(N-acetylneuraminyl)-galactosylglucosylceramide_N-acetylgalactosaminyltransferase},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_62bb85cf79eb; sha256 66ef499e73535e634e686e061fb958b8c81690ff4be5cbf3ff1d5935da6a7a8e},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/(N-acetylneuraminyl)-galactosylglucosylceramide_N-acetylgalactosaminyltransferase. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase (EC 2.4.1.92, uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase, ganglioside GM2 synthase, ganglioside GM3 acetylgalactosaminyltransferase, GM2 synthase, UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase, UDP-N-acetyl-D-galactosamine:1-O-[O-(N-acetyl-alpha-neuraminyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]-ceramide 1,4-beta-N-acetyl-D-galactosaminyltransferase acetylgalactosaminyltransferase, UDP-N-acetylgalactosamine GM3 N-acetylgalactosaminyltransferase, uridine diphosphoacetylgalactosamine-acetylneuraminylgalactosylglucosylceramide acetylgalactosaminyltransferase, uridine diphosphoacetylgalactosamine-hematoside acetylgalactosaminyltransferase, GM2/GD2-synthase, beta-1,4N-aetylgalactosaminyltransferase, asialo-GM2 synthase, GalNAc-T, UDP-N-acetyl-D-galactosamine:(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetyl-D-galactosaminyltransferase) is an enzyme with systematic name UDP-N-acetyl-D-galactosamine:1-O-(O-(N-acetyl-alpha-neuraminyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl)-ceramide 4-beta-N-acetyl-D-galactosaminyltransferase. This enzyme catalyses the following chemical reaction: UDP-N-acetyl-D-galactosamine + 1-O-[O-(N-acetyl-alpha-neuraminyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]-ceramide ⇌ {\displaystyle \rightleftharpoons } UDP + 1-O-[O-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl-(1->4)-O-[N-acetyl-alpha-neuraminyl-(2->3)]-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]-ceramide This enzyme catalyses the formation of the gangliosides (i.e. sialic-acid-containing glycosphingolipids) GM2, GD2 and SM2 from GM3, GD3 and SM3, respectively.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase» — https://en.wikipedia.org/wiki/(N-acetylneuraminyl)-galactosylglucosylceramide_N-acetylgalactosaminyltransferase
Wikidata Q6362619: «class of enzymes» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q6362619
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/(N-acetylneuraminyl)-galactosylglucosylceramide_N-acetylgalactosaminyltransferase?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1306523742, consultata il 2026-10-06T09:59:52.465Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 9dabb5b4cec40ba28a5a41a73976c7e09dcf152160438a9e2453adcfe4b56f28