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Changes in genital Human Papillomavirus (HPV) prevalence among urban females a decade after the Malaysian HPV vaccination program — Europe PMC PMID:36538522

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/36538522
DOI: 10.1371/journal.pone.0278477
License (as archived): CC0-1.0
Archived: 2026-10-08T17:14:03.062Z
SHA-256 of the archived text: 3cb0247b2f5f0ac632a2c8b0c3bad440f61bc6239a8ed235cb05d4b0ff49a0b9
Stable URL of this page: https://metraipolis.com/documento/dc_504dd4e33d34

How to cite

Changes in genital Human Papillomavirus (HPV) prevalence among urban females a decade after the Malaysian HPV vaccination program — Europe PMC PMID:36538522 — Europe PMC (en), https://europepmc.org/article/MED/36538522 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_504dd4e33d34 (Metraipolis archive dc_504dd4e33d34, sha256 3cb0247b2f5f0ac632a2c8b0c3bad440f61bc6239a8ed235cb05d4b0ff49a0b9)

BibTeX

@misc{dc504dd4e33d34,
  title = {Changes in genital Human Papillomavirus (HPV) prevalence among urban females a decade after the Malaysian HPV vaccination program — Europe PMC PMID:36538522},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/36538522},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_504dd4e33d34; sha256 3cb0247b2f5f0ac632a2c8b0c3bad440f61bc6239a8ed235cb05d4b0ff49a0b9},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/36538522. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

To increase the coverage of HPV vaccination, Malaysia implemented a national school-based vaccination program for all 13-year-old girls in 2010. Two years later, a clinic-based catch-up program was started for 16 to 21-year-old girls. We assessed the prevalence of a range of HPV genotypes, among a sample of urban women within the age groups of 18-24 and 35-45 years in 2019-2020, a decade into the national vaccination program. The HPV prevalence was then compared to that reported in an unvaccinated population in 2013-2015. We sampled a total of 1134 participants, comprising of 277 women aged 18-24 years and 857 women aged 35-45 years, from several urban clinics in the state of Selangor. Participants provided a self-acquired vaginal sample for HPV genotyping. Comprehensive sociodemographic and vaccination history were collected. The HPV vaccination coverage among women in the younger age group increased from 9.3% in 2013-2015 to 75.5% in 2019-2020. The prevalence of vaccine-targeted HPV16/18 decreased 91% (CI: 14.5%-99.0%) among the younger women, from 4.0% in 2013-2015 to 0.4% in 2019-2020. There was also an 87% (CI: 27.5%-97.5%) reduction in HPV6/11/16/18. There was no difference in the prevalence of non-vaccine targeted HPV genotypes among younger women. The HPV prevalence among older women, for both vaccine targeted and non-vaccine targeted genotypes in 2019-2020, did not differ from 2013-2015. The observed decline in prevalence of vaccine-targeted HPV genotype among younger women a decade after the national HPV vaccination program is an early indication of its effectiveness in reducing the burden of cervical cancer.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: PloS one, 2022 (prima pubblicazione 2022-12-20).
Identificativi: PMID 36538522 · PMCID PMC9767374 · DOI 10.1371/journal.pone.0278477.
Descrittori MeSH principali: Papillomavirus Infections; Uterine Cervical Neoplasms; Papillomavirus Vaccines.
Pagina: https://europepmc.org/article/MED/36538522 — https://doi.org/10.1371/journal.pone.0278477. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-10-08T16:16:44.879Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.