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Retrograde signaling — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Retrograde_signaling
License (as archived): CC-BY-SA-4.0
Archived: 2026-10-31T14:21:58.867Z
SHA-256 of the archived text: 3c6ff637a695af3fe4b33bfe083515796e25fa805007b511683eaaec6f363000
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Retrograde signaling — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Retrograde_signaling (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_43390aba9abe (Metraipolis archive dc_43390aba9abe, sha256 3c6ff637a695af3fe4b33bfe083515796e25fa805007b511683eaaec6f363000)

BibTeX

@misc{dc43390aba9abe,
  title = {Retrograde signaling — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Retrograde_signaling},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_43390aba9abe; sha256 3c6ff637a695af3fe4b33bfe083515796e25fa805007b511683eaaec6f363000},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Retrograde_signaling. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Retrograde signaling in biology is the process where a signal travels backwards from a target source back to its original source. Neurons use extended axons that are away from the cell body and dendrites, by using retrograde signaling endosomes, communication can occur. This occurrence happens from the distal part of the axon, the signals then travel to the cell body. Typically, the nucleus of a cell is the original source that creates signaling proteins. However, during retrograde signaling, instead of signals leaving the nucleus, they are sent to the nucleus. Particularly, in cell biology, this type of signaling typically occurs between the mitochondria or chloroplast and the nucleus. Signaling molecules from the mitochondria or chloroplast act on the nucleus to affect nuclear gene expression. In this regard, the chloroplast or mitochondria act as a sensor for internal and external stimuli which activate a signaling pathway. In neuroscience, retrograde signaling (or retrograde neurotransmission) refers more specifically to the process by which a retrograde messenger, such as an anandamide or nitric oxide, is released by a postsynaptic dendrite or cell body, and travels "backwards" across a chemical synapse to bind to the axon terminal of a presynaptic neuron.

Tema degli esploratori: scienze della vita e salute (deposito sistematico; ricerca «cell biology»).
Fonte: Wikipedia in inglese, voce «Retrograde signaling» — https://en.wikipedia.org/wiki/Retrograde_signaling
Wikidata Q7317034 (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q7317034
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Retrograde_signaling?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1369381890, consultata il 2026-10-31T14:11:56.706Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 9df969bc0d8566b37c0ffedf7225739057edd9086352b31d7a5d99fc94672158