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Assessment of Inactivation Procedures for SARS-CoV-2 — Europe PMC PPR:PPR168762

Source
Europe PMC
Original
https://europepmc.org/article/PPR/PPR168762
DOI
10.1101/2020.05.28.120444
License (as archived)
CC0-1.0
Archived
2026-11-08T14:42:01.096Z
SHA-256 of the archived text
63f84c27a94bf56d14001679008ef72f7680263266d6ce5290c9421b3acec61f
Stable URL of this page
https://metraipolis.com/documento/dc_36cd3ebffd12

How to cite

Assessment of Inactivation Procedures for SARS-CoV-2 — Europe PMC PPR:PPR168762 — Europe PMC, https://europepmc.org/article/PPR/PPR168762 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_36cd3ebffd12 (Metraipolis archive dc_36cd3ebffd12, sha256 63f84c27a94bf56d14001679008ef72f7680263266d6ce5290c9421b3acec61f)
BibTeX
@misc{dc36cd3ebffd12,
  title = {Assessment of Inactivation Procedures for SARS-CoV-2 — Europe PMC PPR:PPR168762},
  howpublished = {Europe PMC},
  url = {https://europepmc.org/article/PPR/PPR168762},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_36cd3ebffd12; sha256 63f84c27a94bf56d14001679008ef72f7680263266d6ce5290c9421b3acec61f},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC, https://europepmc.org/article/PPR/PPR168762. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of Coronavirus disease 2019 (COVID-19), presents a challenge to laboratorians and healthcare workers around the world. Handling of biological samples from individuals infected with the SARS-CoV-2 virus requires strict biosafety and biosecurity measures. Within the laboratory, non-propagative work with samples containing the virus requires, at minimum, Biosafety Level-2 (BSL-2) techniques and facilities. Therefore, handling of SARS-CoV-2 samples remains a major concern in areas and conditions where biosafety and biosecurity for specimen handling is difficult to maintain, such as in rural laboratories or austere field testing sites. Inactivation through physical or chemical means can reduce the risk of handling live virus and increase testing ability worldwide. Herein we assess several chemical and physical inactivation techniques employed against SARS-CoV-2 isolates from Cambodian COVID-19 patients. This data demonstrates that all chemical (AVL, inactivating sample buffer and formaldehyde) and heat treatment (56°C and 98°C) methods tested completely inactivated viral loads of up to 5 log 10 .

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: bioRxiv, 2020 (prima pubblicazione 2020-05-28).
Identificativi: DOI 10.1101/2020.05.28.120444.
Pagina: https://europepmc.org/article/PPR/PPR168762 — https://doi.org/10.1101/2020.05.28.120444. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-11-08T14:37:55.127Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.