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3,4-Dihydroxyphenylacetic acid — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/3,4-Dihydroxyphenylacetic_acid
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-06T12:40:39.945Z
SHA-256 of the archived text: 67357138dd51815b46f22acad6f7fea19b3ecda8c705d4d4ae4189f607238e33
Stable URL of this page: https://metraipolis.com/documento/dc_342bf03aa50b

How to cite

3,4-Dihydroxyphenylacetic acid — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/3,4-Dihydroxyphenylacetic_acid (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_342bf03aa50b (Metraipolis archive dc_342bf03aa50b, sha256 67357138dd51815b46f22acad6f7fea19b3ecda8c705d4d4ae4189f607238e33)

BibTeX

@misc{dc342bf03aa50b,
  title = {3,4-Dihydroxyphenylacetic acid — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/3,4-Dihydroxyphenylacetic_acid},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_342bf03aa50b; sha256 67357138dd51815b46f22acad6f7fea19b3ecda8c705d4d4ae4189f607238e33},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/3,4-Dihydroxyphenylacetic_acid. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine. Dopamine can be metabolized into one of three substances. One such substance is DOPAC. Another is 3-methoxytyramine (3-MT). Both of these substances are degraded to form homovanillic acid (HVA). Both degradations involve the enzymes monoamine oxidase (MAO) and catechol-O-methyl transferase (COMT), albeit in reverse order: MAO catalyzes dopamine to DOPAC, and COMT catalyzes DOPAC to HVA; whereas COMT catalyzes dopamine to 3-MT and MAO catalyzes 3-MT to HVA. The third metabolic end-product of dopamine is norepinephrine (noradrenaline). It can also be found in the bark of Eucalyptus globulus. This product has been synthesized (52% yield) from 4-hydroxyphenylacetic acid via aerobic biotransformation using whole cell cultures of Arthrobacter protophormiae.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «3,4-Dihydroxyphenylacetic acid» — https://en.wikipedia.org/wiki/3,4-Dihydroxyphenylacetic_acid
Wikidata Q4634071: «composto chimico» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q4634071
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/3,4-Dihydroxyphenylacetic_acid?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1329181390, consultata il 2026-11-06T12:37:55.556Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 4e41452b59332e4837ba2ad9876c74e3f35329dce3715d67a7bc8f04bf38dc48