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Ancestim — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Ancestim
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-09T01:35:57.268Z
SHA-256 of the archived text: 2a1b6e1ab01880e3bbe8ffaa71ce16f2f81cbfb0ee11dd10b49c60a23e1e4cb1
Stable URL of this page: https://metraipolis.com/documento/dc_2fb11671faec

How to cite

Ancestim — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Ancestim (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_2fb11671faec (Metraipolis archive dc_2fb11671faec, sha256 2a1b6e1ab01880e3bbe8ffaa71ce16f2f81cbfb0ee11dd10b49c60a23e1e4cb1)

BibTeX

@misc{dc2fb11671faec,
  title = {Ancestim — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Ancestim},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_2fb11671faec; sha256 2a1b6e1ab01880e3bbe8ffaa71ce16f2f81cbfb0ee11dd10b49c60a23e1e4cb1},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Ancestim. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Ancestim is a recombinant methionyl human stem cell factor, branded by Amgen as StemGen. It was developed by Amgen and sold to Biovitrium, now Swedish Orphan Biovitrum, in December, 2008. It is a 166 amino acid protein produced by E. coli bacteria into which a gene has been inserted for soluble human stem cell factor. It has a monomeric molecular weight of approximately 18,500 daltons and normally exists as a noncovalently associated dimer. The protein has an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis, except for the addition of an N-terminal methionine retained after expression in E. coli. Because Ancestim is produced in E. coli, it is nonglycosylated. Ancestim is supplied as a sterile, white, preservative-free, lyophilised powder for reconstitution and administration as a subcutaneous (SC) injection and is indicated for use in combination with filgrastim for mobilizing peripheral hematopoietic stem cells for later transplantation in certain cancer patients.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «Ancestim» — https://en.wikipedia.org/wiki/Ancestim
Wikidata Q4752549: «composto chimico» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q4752549
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Ancestim?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1198604793, consultata il 2026-11-09T01:33:07.473Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 505f86155f9ececcc235e71ab414bc9daca3703d3f6301a7857c412134e719e0