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Dietary vitamin E reaches the mitochondria in the flight muscle of zebra finches but only if they exercise — Europe PMC PMID:34181660

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/34181660
DOI: 10.1371/journal.pone.0253264
License (as archived): CC0-1.0
Archived: 2026-11-03T23:17:52.169Z
SHA-256 of the archived text: 08457433945824fe5ecf78d34da582f06f142366fbacb709778a8ed77e6e4e82
Stable URL of this page: https://metraipolis.com/documento/dc_2d5564bee299

How to cite

Dietary vitamin E reaches the mitochondria in the flight muscle of zebra finches but only if they exercise — Europe PMC PMID:34181660 — Europe PMC (en), https://europepmc.org/article/MED/34181660 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_2d5564bee299 (Metraipolis archive dc_2d5564bee299, sha256 08457433945824fe5ecf78d34da582f06f142366fbacb709778a8ed77e6e4e82)

BibTeX

@misc{dc2d5564bee299,
  title = {Dietary vitamin E reaches the mitochondria in the flight muscle of zebra finches but only if they exercise — Europe PMC PMID:34181660},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/34181660},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_2d5564bee299; sha256 08457433945824fe5ecf78d34da582f06f142366fbacb709778a8ed77e6e4e82},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/34181660. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Whether dietary antioxidants are effective for alleviating oxidative costs associated with energy-demanding life events first requires they are successfully absorbed in the digestive tract and transported to sites associated with reactive species production (e.g. the mitochondria). Flying birds are under high energy and oxidative demands, and although birds commonly ingest dietary antioxidants in the wild, the bioavailability of these consumed antioxidants is poorly understood. We show for the first time that an ingested lipophilic antioxidant, α-tocopherol, reached the mitochondria in the flight muscles of a songbird but only if they regularly exercise (60 min of perch-to-perch flights two times in a day or 8.5 km day-1). Deuterated α-tocopherol was found in the blood of exercise-trained zebra finches within 6.5 hrs and in isolated mitochondria from pectoral muscle within 22.5 hrs, but never reached the mitochondria in caged sedentary control birds. This rapid pace (within a day) and extent of metabolic routing of a dietary antioxidant to muscle mitochondria means that daily consumption of such dietary sources can help to pay the inevitable oxidative costs of flight muscle metabolism, but only when combined with regular exercise.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: PloS one, 2021 (prima pubblicazione 2021-06-28).
Identificativi: PMID 34181660 · PMCID PMC8238215 · DOI 10.1371/journal.pone.0253264.
Descrittori MeSH principali: Physical Conditioning, Animal.
Pagina: https://europepmc.org/article/MED/34181660 — https://doi.org/10.1371/journal.pone.0253264. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-11-03T23:03:23.256Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.