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Artificial antigen-presenting cell — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Artificial_antigen-presenting_cell
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-10T01:29:47.000Z
SHA-256 of the archived text: bce6fbedff9c957f85767f3b347cbdcbe8157801327a8a5c11c316d110aaba53
Stable URL of this page: https://metraipolis.com/documento/dc_2ac2e2041bee

How to cite

Artificial antigen-presenting cell — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Artificial_antigen-presenting_cell (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_2ac2e2041bee (Metraipolis archive dc_2ac2e2041bee, sha256 bce6fbedff9c957f85767f3b347cbdcbe8157801327a8a5c11c316d110aaba53)

BibTeX

@misc{dc2ac2e2041bee,
  title = {Artificial antigen-presenting cell — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Artificial_antigen-presenting_cell},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_2ac2e2041bee; sha256 bce6fbedff9c957f85767f3b347cbdcbe8157801327a8a5c11c316d110aaba53},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Artificial_antigen-presenting_cell. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Artificial antigen presenting cells (aAPCs) are engineered platforms designed to mimic the function of natural antigen-presenting cells (APCs) in stimulating T-cell responses. They are an emerging technology in cancer immunotherapy, which aims to harness the immune system to recognize and eliminate mutated cancer cells in a manner similar to how the body defends against viruses and other infectious agents. Natural APCs act as sentinels of the immune system, patrolling the body for pathogens. When a pathogen is encountered, these cells activate T cells—often described as the "soldiers" of the immune system—by delivering specific stimulatory signals via cell surface molecules (epitopes). aAPCs replicate this process synthetically by attaching T-cell-activating signals to biocompatible surfaces, such as micron-sized beads or other macro- and microscale materials. By imitating the antigen-presenting function of natural APCs, aAPCs allow for controlled activation and expansion of functional, pathogen- or tumor-specific T cells. These activated T cells can be studied in a biomimetic context and used for adoptive cell transfer therapies. aAPCs also offer potential advantages over natural APCs, including scalable production, lower cost, and enhanced experimental control.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «Artificial antigen-presenting cell» — https://en.wikipedia.org/wiki/Artificial_antigen-presenting_cell
Wikidata Q25323698 (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q25323698
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Artificial_antigen-presenting_cell?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1342171850, consultata il 2026-11-10T01:26:57.553Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 3061a2e2835b58036df75a86056d7a2945e5b1061b0f16bdeac091b81e7835ea