Metraipolis › archive › dc_2ab34adc8aaf

Antiandrogen — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Antiandrogen
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-09T14:20:41.292Z
SHA-256 of the archived text: 3068626441385fbc9d84af405d0d93026f069653b092f8842de2eb483675afb3
Stable URL of this page: https://metraipolis.com/documento/dc_2ab34adc8aaf

How to cite

Antiandrogen — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Antiandrogen (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_2ab34adc8aaf (Metraipolis archive dc_2ab34adc8aaf, sha256 3068626441385fbc9d84af405d0d93026f069653b092f8842de2eb483675afb3)

BibTeX

@misc{dc2ab34adc8aaf,
  title = {Antiandrogen — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Antiandrogen},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_2ab34adc8aaf; sha256 3068626441385fbc9d84af405d0d93026f069653b092f8842de2eb483675afb3},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Antiandrogen. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body. They act by blocking the androgen receptor (AR) and/or inhibiting or suppressing androgen production. They can be thought of as the functional opposites of AR agonists, for instance androgens and anabolic steroids (AAS) like testosterone, DHT, and nandrolone and selective androgen receptor modulators (SARMs) like enobosarm. Antiandrogens are one of three types of sex hormone antagonists, the others being antiestrogens and antiprogestogens. Antiandrogens are used to treat an assortment of androgen-dependent conditions. In men, antiandrogens are used in the treatment of prostate cancer, enlarged prostate, scalp hair loss, overly high sex drive, unusual and problematic sexual urges, and early puberty. In women, antiandrogens are used to treat acne, seborrhea, excessive hair growth, scalp hair loss, and high androgen levels, such as those that occur in polyendocrine metabolic ovarian syndrome (PMOS). Antiandrogens are also used as a component of feminizing hormone therapy for transgender women and as puberty blockers in transgender girls. Side effects of antiandrogens depend on the type of antiandrogen and the specific antiandrogen in question. In any case, common side effects of antiandrogens in men include breast tenderness, breast enlargement, feminization, hot flashes, sexual dysfunction, infertility, and osteoporosis. In women, antiandrogens are much better tolerated, and antiandrogens that work only by directly blocking androgens are associated with minimal side effects. However, because estrogens are made from androgens in the body, antiandrogens that suppress androgen production can cause low estrogen levels and associated symptoms like hot flashes, menstrual irregularities, and osteoporosis in premenopausal women. There several major classes of antiandrogens. These include AR antagonists, androgen synthesis inhibitors, and antigonadotropins. AR antagonists work by directly blocking the effects of androgens, while androgen synthesis inhibitors and antigonadotropins work by lowering androgen levels. AR antagonists can be further divided into steroidal antiandrogens and nonsteroidal antiandrogens; androgen synthesis inhibitors can be further divided mostly into CYP17A1 inhibitors and 5α-reductase inhibitors; and antigonadotropins can be further divided into gonadotropin-releasing hormone modulators (GnRH modulators), progestogens, and estrogens.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «Antiandrogen» — https://en.wikipedia.org/wiki/Antiandrogen
Wikidata Q574820: «farmaci che inibiscono gli effetti degli ormoni sessuali maschili» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q574820
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Antiandrogen?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1384373729, consultata il 2026-11-09T14:17:16.222Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 2e5dd6c2dba2b3153a74d68773334fba4b38b53559a3590391069619ca45c300