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4-PPBP — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/4-PPBP
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-06T15:52:07.133Z
SHA-256 of the archived text: 2bfb48b2867ffc05da957bcf3468f58da56fa8d1dde0aa8791e7e64125d99536
Stable URL of this page: https://metraipolis.com/documento/dc_293f62fb98ea

How to cite

4-PPBP — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/4-PPBP (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_293f62fb98ea (Metraipolis archive dc_293f62fb98ea, sha256 2bfb48b2867ffc05da957bcf3468f58da56fa8d1dde0aa8791e7e64125d99536)

BibTeX

@misc{dc293f62fb98ea,
  title = {4-PPBP — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/4-PPBP},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_293f62fb98ea; sha256 2bfb48b2867ffc05da957bcf3468f58da56fa8d1dde0aa8791e7e64125d99536},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/4-PPBP. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

4-PPBP is a neuroprotective cyclic amine which binds to sigma receptors. 4-PPBP decreases neuronal nitric oxide synthase (nNOS) activity and ischemia-evoked nitric oxide (NO) production. 4-PPBP provides neuroprotection; this involves the prevention of ischemia-induced intracellular Ca2+ dysregulation. 4-PPBP protects neurons using a mechanism that activates the transcription factor cyclic adenosine monophosphate response element-binding protein (CREB). Neuroprotection that is associated with 4-PPBP increases Bcl-2 expression; Bcl-2 expression is regulated by CREB.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «4-PPBP» — https://en.wikipedia.org/wiki/4-PPBP
Wikidata Q4637191: «composto chimico» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q4637191
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/4-PPBP?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1383462966, consultata il 2026-11-06T15:43:12.168Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 35999cde0ca3f3a88211f84cf6ea866c53ccb8587dc3e93f5003f7d7a06466f4