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Alessandro Sette — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Alessandro_Sette
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-08T06:03:28.617Z
SHA-256 of the archived text: 52ad0a1427a85457555ba090d76d7f95a80f41a45cbe5484020ef3259acb110c
Stable URL of this page: https://metraipolis.com/documento/dc_25ed351cd337

How to cite

Alessandro Sette — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Alessandro_Sette (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_25ed351cd337 (Metraipolis archive dc_25ed351cd337, sha256 52ad0a1427a85457555ba090d76d7f95a80f41a45cbe5484020ef3259acb110c)

BibTeX

@misc{dc25ed351cd337,
  title = {Alessandro Sette — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Alessandro_Sette},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_25ed351cd337; sha256 52ad0a1427a85457555ba090d76d7f95a80f41a45cbe5484020ef3259acb110c},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Alessandro_Sette. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Alessandro Sette is an Italian immunologist. He was born on August 11, 1960, in Rome, Italy, to Pietro Sette, a prominent Italian businessman and politician, and Renata Sette. Sette is a professor at the La Jolla Institute for Immunology (LJI). He is an adjunct professor at the University of California, San Diego. Sette studies the specific epitopes that the immune system recognizes in cancer, autoimmunity, allergy, and infectious diseases. In 1988, Sette moved to San Diego to conduct research at San Diego biotech Cytel. He then co-founded Epimmune. In 2003, Sette joined the faculty of the La Jolla Institute for Immunology. In 2003, Sette founded and currently co-leads the Immune Epitope Database (IEDB), an NIAID-funded online database that catalogues epitopes involved in immune system recognition of allergens, infectious diseases, autoantigens, and transplanted tissue in humans and various species. In 2020, Sette published the first study of SARS-CoV-2 epitopes targeted by the human immune system. He has co-led research into CD8+ and CD4+ T cell responses in COVID-19 patients and studied CD8+ T cell cross-reactivity to SARS-CoV-2 epitopes and other coronaviruses. In 2025, Sette and colleagues published findings indicating that patients with amyotrophic lateral sclerosis (ALS) exhibit adaptive immune responses targeting the C9orf72 protein, a common genetic contributor to the disease. The study reported enhanced CD4⁺ T-cell activity and cytokine production in ALS patients compared to controls, suggesting that autoimmune mechanisms may contribute to ALS disease pathology and progression. Throughout his career, Sette has maintained strong scientific ties with Italy and currently is a Member of the Scientific Council of ISSNAF, a not-for-profit organization whose mission is to connect, empower and celebrate the Italian Intellectual Diaspora in North America. He was recently named as a Member of ISNAFF's Board of Directors. In 2025, Sette was awarded the title of "Cavaliere dell'Ordine al Merito della Repubblica Italiana" in recognition of his contributions to biomedical science and global health.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «Alessandro Sette» — https://en.wikipedia.org/wiki/Alessandro_Sette
Wikidata Q28324161: «ricercatore» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q28324161
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Alessandro_Sette?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1374843643, consultata il 2026-11-08T05:59:03.140Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 661e6b0c563c8125484ea932faeda910694d71a73da0a064bb748427b985233b