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ASXL1 — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/ASXL1
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-07T01:06:33.001Z
SHA-256 of the archived text: cb586acf5b04e54dbc3a185c0004369cac7072028be7c0c1cdec04c68a3e757f
Stable URL of this page: https://metraipolis.com/documento/dc_236205eb97dc

How to cite

ASXL1 — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/ASXL1 (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_236205eb97dc (Metraipolis archive dc_236205eb97dc, sha256 cb586acf5b04e54dbc3a185c0004369cac7072028be7c0c1cdec04c68a3e757f)

BibTeX

@misc{dc236205eb97dc,
  title = {ASXL1 — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/ASXL1},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_236205eb97dc; sha256 cb586acf5b04e54dbc3a185c0004369cac7072028be7c0c1cdec04c68a3e757f},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/ASXL1. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Putative Polycomb group protein ASXL1 is a protein that in humans is encoded by the ASXL1 gene. In Drosophila, the Additional sex combs (Asx) gene encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «ASXL1» — https://en.wikipedia.org/wiki/ASXL1
Wikidata Q18052988: «protein-coding gene in the species Homo sapiens» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q18052988
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/ASXL1?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1330370538, consultata il 2026-11-07T01:02:56.800Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: a04cc873494c8fe7a7d0b844dcee7e6a6e9ade7485cfb5944efa0480aa4b6d51