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A computational study to model the effect of electrode-to-auditory nerve fiber distance on spectral resolution in cochlear implant — Europe PMC PMID:32745116

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/32745116
DOI: 10.1371/journal.pone.0236784
License (as archived): CC0-1.0
Archived: 2026-11-07T21:14:35.490Z
SHA-256 of the archived text: ebf9fed05fb668c5ac42801ad54fb221d6ccdd9039562aa34b05bfff412a965c
Stable URL of this page: https://metraipolis.com/documento/dc_203dafc4fcff

How to cite

A computational study to model the effect of electrode-to-auditory nerve fiber distance on spectral resolution in cochlear implant — Europe PMC PMID:32745116 — Europe PMC (en), https://europepmc.org/article/MED/32745116 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_203dafc4fcff (Metraipolis archive dc_203dafc4fcff, sha256 ebf9fed05fb668c5ac42801ad54fb221d6ccdd9039562aa34b05bfff412a965c)

BibTeX

@misc{dc203dafc4fcff,
  title = {A computational study to model the effect of electrode-to-auditory nerve fiber distance on spectral resolution in cochlear implant — Europe PMC PMID:32745116},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/32745116},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_203dafc4fcff; sha256 ebf9fed05fb668c5ac42801ad54fb221d6ccdd9039562aa34b05bfff412a965c},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/32745116. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Spectral ripple discrimination (SRD) has been widely used to evaluate the spectral resolution in cochlear implant (CI) recipients based on its strong correlation with speech perception performance. However, despite its usefulness for predicting speech perception outcomes, SRD performance exhibits large across-subject variabilities even among subjects implanted with the same CIs and sound processors. The potential factors of this observation include current spread, nerve survival, and CI mapping. Previous studies have found that the spectral resolution reduces with increasing distance of the stimulation electrode from the auditory nerve fibers (ANFs), attributable to increasing current spread. However, it remains unclear whether the spread of excitation is the only cause of the observation, or whether other factors such as temporal interaction also contribute to it. In this study, we used a computational model to investigate channel interaction upon non-simultaneous stimulation with respect to the electrode-ANF distance, and evaluated the SRD performance for five electrode-ANF distances. The SRD performance was determined based on the similarity between two neurograms in response to standard and inverted stimuli and used to evaluate the spectral resolution in the computational model. The spread of excitation was observed to increase with increasing electrode-ANF distance, consistent with previous findings. Additionally, the preceding pulses delivered from neighboring channels induced a channel interaction that either inhibited or facilitated the neural responses to subsequent pulses depending on the electrode-ANF distance. The SRD performance was also found to decrease with increasing electrode-ANF distance. The findings of this study suggest that variation of the neural responses (inhibition or facilitation) with the electrode-ANF distance in CI users may cause spectral smearing, and hence poor spectral resolution. A computational model such as that used in this study is a useful tool for understanding the neural factors related to CI outcomes, such as cannot be accomplished by behavioral studies alone.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: PloS one, 2020 (prima pubblicazione 2020-08-03).
Identificativi: PMID 32745116 · PMCID PMC7398541 · DOI 10.1371/journal.pone.0236784.
Descrittori MeSH principali: Cochlear Implants.
Pagina: https://europepmc.org/article/MED/32745116 — https://doi.org/10.1371/journal.pone.0236784. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-11-07T21:10:38.825Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.