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Animal models of Parkinson's disease — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Animal_models_of_Parkinson%27s_disease
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-09T08:28:25.958Z
SHA-256 of the archived text: 9ca93eb3f2580f8aef8b778cae536db4c9f2d3f27873f84da3d0779db71905f6
Stable URL of this page: https://metraipolis.com/documento/dc_1fcbec4e035f

How to cite

Animal models of Parkinson's disease — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Animal_models_of_Parkinson%27s_disease (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_1fcbec4e035f (Metraipolis archive dc_1fcbec4e035f, sha256 9ca93eb3f2580f8aef8b778cae536db4c9f2d3f27873f84da3d0779db71905f6)

BibTeX

@misc{dc1fcbec4e035f,
  title = {Animal models of Parkinson's disease — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Animal_models_of_Parkinson%27s_disease},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_1fcbec4e035f; sha256 9ca93eb3f2580f8aef8b778cae536db4c9f2d3f27873f84da3d0779db71905f6},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Animal_models_of_Parkinson%27s_disease. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Animal models of Parkinson's disease are essential in the research field and widely used to study Parkinson's disease. Parkinson's disease is a neurodegenerative disorder, characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The loss of the dopamine neurons in the brain, results in motor dysfunction, ultimately causing the four cardinal symptoms of PD: tremor, rigidity, postural instability, and bradykinesia. It is the second most prevalent neurodegenerative disease, following Alzheimer's disease. It is estimated that nearly one million people could be living with PD in the United States. There are a variety of models that can be utilized to be able to address important aspects of Parkinson's disease. Researchers can consider disease progression, cell death, behavioral characteristics, and more PD phenotypes. Parkinson's disease animal models are divided into two categories: neurotoxin models and genetic models. Neurotoxin models include chemically induced toxicity in the brain; whereas, genetic models include genes that are mutated and induce PD phenotypes.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «Animal models of Parkinson's disease» — https://en.wikipedia.org/wiki/Animal_models_of_Parkinson%27s_disease
Wikidata Q104855963: «models used in Parkinson's disease research» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q104855963
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Animal_models_of_Parkinson%27s_disease?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1380742975, consultata il 2026-11-09T08:22:12.288Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 8f05ebda64523ee6b9d0e7e661ddf9c55f92376ee68ee792b10dae4bd1852b4e