Metraipolis › archive › dc_130fcaabc79b

Characteristics associated with viral suppression among HIV-infected children aged 0-14 years in Mozambique, 2019 — Europe PMC PMID:39024349

Source: Europe PMC (en)
Original: https://europepmc.org/article/MED/39024349
DOI: 10.1371/journal.pone.0305380
License (as archived): CC0-1.0
Archived: 2026-10-06T16:55:42.193Z
SHA-256 of the archived text: 6f4e512b9e33c6fcd91b5b540f3395f81857b6ca2e67f42f6fbc092249e7abad
Stable URL of this page: https://metraipolis.com/documento/dc_130fcaabc79b

How to cite

Characteristics associated with viral suppression among HIV-infected children aged 0-14 years in Mozambique, 2019 — Europe PMC PMID:39024349 — Europe PMC (en), https://europepmc.org/article/MED/39024349 (CC0-1.0); archived copy: https://metraipolis.com/documento/dc_130fcaabc79b (Metraipolis archive dc_130fcaabc79b, sha256 6f4e512b9e33c6fcd91b5b540f3395f81857b6ca2e67f42f6fbc092249e7abad)

BibTeX

@misc{dc130fcaabc79b,
  title = {Characteristics associated with viral suppression among HIV-infected children aged 0-14 years in Mozambique, 2019 — Europe PMC PMID:39024349},
  howpublished = {Europe PMC (en)},
  url = {https://europepmc.org/article/MED/39024349},
  note = {License CC0-1.0; archived copy https://metraipolis.com/documento/dc_130fcaabc79b; sha256 6f4e512b9e33c6fcd91b5b540f3395f81857b6ca2e67f42f6fbc092249e7abad},
  year = {2026}
}

Archived text

Reproduced under CC0-1.0. Attribution: Europe PMC (en), https://europepmc.org/article/MED/39024349. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

The human immunodeficiency virus (HIV) is a global public health problem, disproportionally affecting sub-Saharan African countries including Mozambique. In 2019, of 150,000 estimated HIV-infected children in Mozambique, only 95,080 were on antiretroviral treatment and 73% virally suppressed. The objective of this study was to determine the characteristics associated with viral suppression in children. A cross-sectional study was carried out using records of viral load samples from children aged 0 to 14 years old who underwent viral load tests in 2019 in Mozambique. Secondary analyses were conducted on data obtained from Data Intensive Systems and Applications (DISA) of children enrolled in health facilities who had viral load tests registered. Viral suppression was defined as the presence of less than 1,000 copies/ml of blood. Multivariate logistic regression analysis was used to evaluate the characteristics associated with viral suppression. Of the 33,559 viral load sample records analyzed, 53% (17,794/33,559) were female. The average patient age was 8 (sd ± 4) years old. About 44% (14,888/33,559) of the children had a suppressed viral load, with 55% (8,258/14,888) being female and 16% (2,319/14,888) belonging to the 1-4 years old age group. Characteristics associated with viral suppression were the age groups of 5-9 years [AOR = 1.73; 95% CI 1.34-2.23; p<0.001] and 10-14 years old [AOR = 1.92; 95% CI 1.50-2.48; p<0.001] versus < 1 year. Other factors such as living in Maputo City [AOR = 1.61; 95% CI 1.26-2.05; p <0.001] versus Tete Province were also associated with viral suppression. Factors such as being male [AOR = 0.83; 95% CI 0.80-0.87; p <0.001)], living in the provinces of Niassa [AOR = 0.75; 95% CI 0.56-0.99; p <0.003], Cabo Delgado [AOR = 0.77; 95% CI 0.60-0.99; p <0.045] and Zambezia [AOR = 0.72 (95% CI: 0.56-0.92, p<0.008)] versus Tete Province, or being on ART for 2-5 years [AOR = 0.72 (95% CI: 0.61-0.85, p<0.001)] versus 11-14 years were associated with not being virally suppressed. More than half of children did not achieve viral suppression. The odds of viral suppression were highest among children aged 5-14 years and among children living in Maputo city. Further research is needed to better understand the challenges in achieving viral suppression in children.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (retro-catalogo: tutto il sottoinsieme open access di Europe PMC con licenza libera).
Pubblicazione: PloS one, 2024 (prima pubblicazione 2024-07-18).
Identificativi: PMID 39024349 · PMCID PMC11257270 · DOI 10.1371/journal.pone.0305380.
Descrittori MeSH principali: HIV Infections; Viral Load.
Pagina: https://europepmc.org/article/MED/39024349 — https://doi.org/10.1371/journal.pone.0305380. Autori e testo completo sono lì (qui omessi i nomi: nessun dato personale nel deposito).
Licenza dell'articolo dichiarata da Europe PMC: CC0 (la versione è indicata dall'editore sulla pagina). Abstract riportato senza modifiche al contenuto, con attribuzione; deposito marcato CC0.
Letto il 2026-10-06T15:19:26.867Z tramite l'API REST ufficiale di Europe PMC (EMBL-EBI), nel rispetto del robots.txt e del crawl-delay.