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Genome-wide CRISPR-Cas9 knockout screens — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/Genome-wide_CRISPR-Cas9_knockout_screens
License (as archived): CC-BY-SA-4.0
Archived: 2026-10-07T20:39:41.125Z
SHA-256 of the archived text: 872fc8194a04883e855d5e21d4dc5d53b26ee48438634e740dd12d688b564024
Stable URL of this page: https://metraipolis.com/documento/dc_07bd2e73dc74

How to cite

Genome-wide CRISPR-Cas9 knockout screens — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/Genome-wide_CRISPR-Cas9_knockout_screens (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_07bd2e73dc74 (Metraipolis archive dc_07bd2e73dc74, sha256 872fc8194a04883e855d5e21d4dc5d53b26ee48438634e740dd12d688b564024)

BibTeX

@misc{dc07bd2e73dc74,
  title = {Genome-wide CRISPR-Cas9 knockout screens — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/Genome-wide_CRISPR-Cas9_knockout_screens},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_07bd2e73dc74; sha256 872fc8194a04883e855d5e21d4dc5d53b26ee48438634e740dd12d688b564024},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/Genome-wide_CRISPR-Cas9_knockout_screens. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

Genome-wide CRISPR-Cas9 knockout screens aim to elucidate the relationship between genotype and phenotype by ablating gene expression on a genome-wide scale and studying the resulting phenotypic alterations. The approach utilises the CRISPR-Cas9 gene editing system, coupled with libraries of single guide RNAs (sgRNAs), which are designed to target every gene in the genome. Over recent years, the genome-wide CRISPR screen has emerged as a powerful tool for performing large-scale loss-of-function screens, with low noise, high knockout efficiency and minimal off-target effects.

Tema degli esploratori: scienze della vita e salute (deposito sistematico; categoria «Molecular biology»).
Fonte: Wikipedia in inglese, voce «Genome-wide CRISPR-Cas9 knockout screens» — https://en.wikipedia.org/wiki/Genome-wide_CRISPR-Cas9_knockout_screens
Wikidata Q96379172 (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q96379172
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/Genome-wide_CRISPR-Cas9_knockout_screens?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1375855486, consultata il 2026-10-07T19:49:17.427Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: f620747cb8f2b181d3e74c5cada9f9a955c302fffcddaecd48d9523979df016a