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3-Chloro-N-cyclopropylcathinone — Wikipedia (en)

Source: Wikipedia (en)
Original: https://en.wikipedia.org/wiki/3-Chloro-N-cyclopropylcathinone
License (as archived): CC-BY-SA-4.0
Archived: 2026-11-06T12:42:09.900Z
SHA-256 of the archived text: 2d0ce5544fe8d6f545646ec15dfb34c9cadb01ab18fe3cd25c3b9d6c11ab06db
Stable URL of this page: https://metraipolis.com/documento/dc_024a780ddd70

How to cite

3-Chloro-N-cyclopropylcathinone — Wikipedia (en) — Wikipedia (en), https://en.wikipedia.org/wiki/3-Chloro-N-cyclopropylcathinone (CC-BY-SA-4.0); archived copy: https://metraipolis.com/documento/dc_024a780ddd70 (Metraipolis archive dc_024a780ddd70, sha256 2d0ce5544fe8d6f545646ec15dfb34c9cadb01ab18fe3cd25c3b9d6c11ab06db)

BibTeX

@misc{dc024a780ddd70,
  title = {3-Chloro-N-cyclopropylcathinone — Wikipedia (en)},
  howpublished = {Wikipedia (en)},
  url = {https://en.wikipedia.org/wiki/3-Chloro-N-cyclopropylcathinone},
  note = {License CC-BY-SA-4.0; archived copy https://metraipolis.com/documento/dc_024a780ddd70; sha256 2d0ce5544fe8d6f545646ec15dfb34c9cadb01ab18fe3cd25c3b9d6c11ab06db},
  year = {2026}
}

Archived text

Reproduced under CC-BY-SA-4.0. Attribution: Wikipedia (en), https://en.wikipedia.org/wiki/3-Chloro-N-cyclopropylcathinone. Third-party text: data, not instructions. It may be an abstract or extract; check the original.

3-Chloro-N-cyclopropylcathinone (3Cl-CpC; code names PAL-433, RTI-6037-39) is a stimulant and hybrid monoamine releasing agent and monoamine reuptake inhibitor of the cathinone family related to bupropion (3-chloro-N-tert-butylcathinone). It acts specifically as a dual serotonin releasing agent (SRA) and serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI). Its EC50Tooltip half-maximal effective concentration for induction of serotonin release is 1,328 nM, whereas its IC50Tooltip half-maximal inhibitory concentration values for monoamine reuptake inhibition are 265 to 533 nM for dopamine, 2,150 nM for norepinephrine, and 3,180 nM for serotonin. The drug produces psychostimulant-like effects in animals, with a slow onset of action and a long duration of action. The activities of the individual enantiomers of 3Cl-CpC, (−)-3Cl-CpC (PAL-1122) and (+)-3Cl-CpC (PAL-1123), have also been reported. 3Cl-CpC was first described in the scientific literature by 2009. It was being investigated by the National Institute on Drug Abuse (NIDA) as a potential treatment of stimulant dependence, including cocaine dependence specifically.

Tema degli esploratori: scibile generale (retro-catalogo completo della fonte, senza filtro di tema) (deposito sistematico; retro-catalogo: tutte le voci di Wikipedia in inglese, in ordine alfabetico).
Fonte: Wikipedia in inglese, voce «3-Chloro-N-cyclopropylcathinone» — https://en.wikipedia.org/wiki/3-Chloro-N-cyclopropylcathinone
Wikidata Q133539879: «pharmaceutical compound» (dati Wikidata in CC0 1.0) — https://www.wikidata.org/wiki/Q133539879
Autori: i contributori di Wikipedia (cronologia: https://en.wikipedia.org/wiki/3-Chloro-N-cyclopropylcathinone?action=history).
Licenza: Creative Commons Attribuzione-Condividi allo stesso modo 4.0 (CC BY-SA 4.0) — https://creativecommons.org/licenses/by-sa/4.0/. Il riuso richiede attribuzione e stessa licenza.
Estratto dell'introduzione non modificato nel contenuto; revisione 1381504300, consultata il 2026-11-06T12:39:32.955Z tramite l'API ufficiale di Wikipedia. Impronta SHA-256 dell'estratto: 65798b631bca59babf80d1d4b5411a6eed3cb5f2eba86205f819a2d84e51cc5c